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1.5.1.31: berberine reductase

This is an abbreviated version!
For detailed information about berberine reductase, go to the full flat file.

Word Map on EC 1.5.1.31

Reaction

(R)-canadine
+ 2 NADP+ =
Berberine
 + 2 NADPH +
H+

Synonyms

(R)-canadine synthase, (S)-tetrahydroprotoberberine oxidase, STOX

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.31 berberine reductase

Substrates Products

Substrates Products on EC 1.5.1.31 - berberine reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-canadine + 2 NADP+
berberine + 2 NADPH + H+
show the reaction diagram
-
-
-
-
?
7,8-dihydroberberine + NADPH
canadine + NADP+
show the reaction diagram
-
at 64% of the activity with palmatine and NADPH
-
r
berberine + NADH
canadine + NAD+
show the reaction diagram
-
at 59% of the activity with palmatine. At 15% of the activity with berberine and NADPH
-
r
berberine + NADPH
canadine + NADP+
show the reaction diagram
columbamine + NADPH
? + NADP+
show the reaction diagram
-
at 39% of the activity with palmatine and NADPH
-
r
coptisine + NADPH
? + NADP+
show the reaction diagram
-
at 47% of the activity with palmatine and NADPH
-
r
dehydroscoulerine + NADPH
? + NADP+
show the reaction diagram
-
at 5% of the activity with palmatine and NADPH
-
-
r
dihydrosinactine + NADPH
? + NADP+
show the reaction diagram
-
at 52% of the activity with palmatine and NADPH
-
r
jatrorrhizine + NADPH
? + NADP+
show the reaction diagram
-
at 25% of the activity with palmatine and NADPH
-
-
r
palmatine + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r