1.5.1.21: 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
This is an abbreviated version!
For detailed information about 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH), go to the full flat file.
Reaction
Synonyms
1,2-didehydropipecolate reductase, 1,2-didehydropipecolic reductase, CRYM, DELTA1-piperideine-2-carboxylate reductase, DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase, DELTA1-pyrroline-2-carboxylate reductase, DpkA, EC 1.5.1.14, ketimine reductase, L-pipecolate:NADP+ 2-oxidoreductase, lhpD, mu-crystallin, NAD(P)H-dependent DELTA1-pyrroline-2-carboxylate reductase, P2C reductase, P2C/Pyr2C reductase, PaLhpD, Pip2CR, Pyr2C reductase, Pyr2C/Pip2C reductase, reductase, DELTA 1-piperideine-2-carboxylate
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Natural Substrates Products
Natural Substrates Products on EC 1.5.1.21 - 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
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REACTION DIAGRAM
1-pyrroline-(4R)-hydroxy-2-carboxylate + NADPH + H+
(4R)-hydroxy-L-proline + NADP+
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-
-
r
1-piperideine-2-carboxylate + NADPH + H+
L-pipecolate + NADP+
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-
-
r
1-pyrroline-2-carboxylate + NADPH + H+
L-proline + NADP+
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-
-
r
L-pipecolate + NADP+
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-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
-
-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
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-
-
r
DELTA1-piperideine 2-carboxylate + NADPH + H+
L-pipecolate + NADP+
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-
-
r
DELTA1-piperideine-2-carboxylate + NADH
L-pipecolate + NAD+
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-
-
-
?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
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D-lysine metabolism
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?
DELTA1-piperideine-2-carboxylate + NADPH
L-pipecolate + NADP+
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?
?
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the same enzyme catalyzes the reduction of both DELTA1-piperideine-2-carboxylate and DELTA1-pyrrolidine-2-carboxylate, but is unable to catalyze the reduction of DELTA1-pyrroline-5-carboxylate and DELTA1-piperideine-6-carboxylate, which may be regarded as double bond positional isomers of DELTA1-piperideine-2-carboxylate and DELTA1-pyrrolidine-2-carboxylate, respectively
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additional information
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enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
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?
additional information
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enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
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-
?
additional information
?
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enzyme is involved in the catabolism of D-lysine and D-proline, pathway overview
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?