1.5.1.2: pyrroline-5-carboxylate reductase
This is an abbreviated version!
For detailed information about pyrroline-5-carboxylate reductase, go to the full flat file.
Reaction
Synonyms
1-pyrroline-5-carboxylate reductase, aldimine reductase, DELTA1-pyrroline-5-carboxylate reductase, DELTA1-pyrroline-5-carboxylate reductase 2, L-proline oxidase, L-proline-NAD(P)+ 5-oxidoreductase, L-proline:NAD(P)+ 5-oxidoreductase, MTR_7g090160, NADPH-L-DELTA'-pyrroline carboxylic acid reductase, P5C reductase, P5CDH, P5CR, PO, POX, PROC, proline oxidase, Pycr1, PYCR2, Pyr5C reductase, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylate reductase, reductase, pyrroline-5-carboxylate, TcCLB.509207.90
ECTree
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Cofactor
Cofactor on EC 1.5.1.2 - pyrroline-5-carboxylate reductase
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NAD+
2fold preference for NADP+ with apparent KM 0.172 mM over NAD+ with apparent KM 0.3896 mM
NADH
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with NADH the activity is markedly inhibited by physiological levels of NADP+, so NADH cannot serve as electron donor in vivo
NADP+
2fold preference for NADP+ with apparent KM 0.172 mM over NAD+ with apparent KM 0.3896 mM
PYCR2 does not show a strong preference for NADH or NADPH
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additional information
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PYCR2 does not show a strong preference for NADH or NADPH
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