Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.1.B4: carboxynorspermidine dehydrogenase

This is an abbreviated version!
For detailed information about carboxynorspermidine dehydrogenase, go to the full flat file.

Reaction

L-aspartic 4-semialdehyde
+
1,3-diaminopropane
+
NADPH
+
H+
=
carboxynorspermidine
+
NADP+
+
H2O

Synonyms

C-NSPD synthase, CANSDH, carboxynorspermidine synthase

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.B4 carboxynorspermidine dehydrogenase

KM Value

KM Value on EC 1.4.1.B4 - carboxynorspermidine dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4.68
L-aspartic 4-semialdehyde
-
pH 7.5, 37°C, Vmax: 35 micromol/min/mg carboxynorspermidine
2.97
NADH
-
pH 7.5, 37°C, with a Vmax of 13.5 micromol carboxynorspermidine/min/mg protein formed
1.51
NADPH
-
pH 7.5, 37°C, with a Vmax of 31 micromol carboxynorspermidine/min/mg protein formed
additional information
additional information
-
the Km for the Schiff base is 4.68 mM, the intermediate formed from L-aspartic 4-semialdehyde and 1,3-diaminopropane, which is reduced to carboxynorspermidine
-