1.3.8.7: medium-chain acyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about medium-chain acyl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.3.8.7

1.3.8.7

carnitine

beta-oxidation

infant

acylcarnitines

children

peroxisome

urine

mcadd

inborn

error

proliferator-activated

hypoglycemia

acidurias

triglyceride

flavoproteins

fad

phenylketonuria

octanoylcarnitine

palmitoyltransferase

acidemia

glutaric

octanoyl-coa

octanoic

hypoketotic

nbs

vlcad

decompensation

coma

pparalpha

methylmalonic

isovaleric

very-long-chain

decanoic

isovaleryl-coa

syrup

reye-like

lethargy

3-hydroxyacyl-coa

maple

homocystinuria

guthrie

biotinidase

acadvl

3-methylcrotonyl-coa

phenylpropionic

butyryl-coa

alpha-proton

medicine

analysis

Reaction

a medium-chain trans-2,3-dehydroacyl-CoA

Synonyms

ACAD-9, ACADM, ACD, acyl CoA dehydrogenase, acyl coenzyme A dehydrogenase, acyl dehydrogenase, acyl-CoA dehydrogenase, acyl-CoA dehydrogenase-9, dehydrogenase, acyl coenzyme A, EC 1.3.2.2, EC 1.3.99.3, FadE, fatty acyl coenzyme A dehydrogenase, fatty-acyl-CoA dehydrogenase, general ACAD, general acyl CoA dehydrogenase, LCAD, LipB, MCAD, MCADH, medium chain acyl-CoA dehydrogenase, medium chain-specific acyl-CoA oxidase, medium-chain acyl CoA dehydrogenase, medium-chain acyl-CoA dehydrogenase, medium-chain acyl-coenzyme A dehydrogenase, medium-chain coenzyme A dehydrogenase, pMCAD, PP_1893, PP_2039, PP_2048, PP_2437

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.8 With a flavin as acceptor

1.3.8.7 medium-chain acyl-CoA dehydrogenase

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Results	in table
2	Activating Compound
12485	AA Sequence
13	Application
1	CAS Registry Number
19	Cloned(Commentary)
28	Cofactor
8	Crystallization (Commentary)
2577	Disease/ Diagnostics
9	General Information
3	General Stability
58	Inhibitors
14	Ki Value [mM]
117	KM Value [mM]
17	Localization
25	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
120	Organism
10	Pathway
4	PDB ID
7	pH Optimum
4	pH Range
1	pH Stability
78	Protein Variants
29	Purification (Commentary)
9	Reaction
5	Reaction Type
114	Reference
73	Source Tissue
19	Specific Activity [micromol/min/mg]
11	Storage Stability
210	Substrates and Products (Substrate)
19	Subunits
83	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
16	Temperature Stability [°C]
84	Turnover Number [1/s]

Purification

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Purification on EC 1.3.8.7 - medium-chain acyl-CoA dehydrogenase

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5 entries

affinity-purified, ca. 95% pure

apoprotein

HiTrap chelating nickel affinity chromatography

recombinant enzyme

recombinant liver enzyme, DEAE-Sephacel, hydroxyapatite, tandem column-chromatography

Homo sapiens

391367

recombinant T168A mutant enzyme

Homo sapiens

391373

recombinant wild-type and K304E mutant enzyme

Homo sapiens

391370

recombinant wild-type, T255E, T255E/E367G and T255E/E367T mutant enzymes

Homo sapiens

391369

wild-type and E376G/T255E double mutant enzyme

Homo sapiens

391368