1.3.5.2: dihydroorotate dehydrogenase (quinone)
This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (quinone), go to the full flat file.
Word Map on EC 1.3.5.2
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1.3.5.2
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pyrimidine
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falciparum
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plasmodium
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leflunomide
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brequinar
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uridine
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malaria
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arthritis
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antimalarial
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rheumatoid
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dihydroorotase
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salvage
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teriflunomide
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dhods
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autoimmune
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orotidine
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ump
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atovaquone
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triazolopyrimidine
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flavoenzyme
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medicine
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phosphoribosyltransferase
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antirheumatic
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coq
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drug development
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decylubiquinone
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dmards
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synthesis
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species-selective
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pyre
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pharmacology
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isoxazole
-
transcarbamoylase
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5-fluoroorotate
- 1.3.5.2
- pyrimidine
- falciparum
- plasmodium
- leflunomide
- brequinar
- uridine
- malaria
- arthritis
-
antimalarial
-
rheumatoid
- dihydroorotase
-
salvage
- teriflunomide
-
dhods
- autoimmune
- orotidine
- ump
- atovaquone
- triazolopyrimidine
-
flavoenzyme
- medicine
-
phosphoribosyltransferase
-
antirheumatic
- coq
- drug development
- decylubiquinone
-
dmards
- synthesis
-
species-selective
-
pyre
- pharmacology
-
isoxazole
-
transcarbamoylase
- 5-fluoroorotate
Reaction
Synonyms
class 2 dihydroorotate dehydrogenases, DHO-DH, DHOD, DHODase, DHODH, dihydroorotate dehydrogenase, EC 1.3.99.11, ETH_00004975, hDHODH, HsDHODH, L-5,6-dihydroorotate:ubiquinone exidoreductase, PfDHODH
ECTree
1.3.5.2 dihydroorotate dehydrogenase (quinone)Advanced search results
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results (KM Value
KM Value on EC 1.3.5.2 - dihydroorotate dehydrogenase (quinone)
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.035
ubiquinone-4
pH 8.0, 25°C, cosubstrate L-dihydroorotate, N-terminally truncated protein
additional information
additional information
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relative Km-values for wild-type and mutants listed for (S)-dihydroorotate and ubiquinone-6
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0.032
decylubiquinone
pH 8.0, 25°C, cosubstrate L-dihydroorotate, N-terminally truncated protein
0.04
dihydroorotate
N-terminally truncated DHODH, fixed concentration of dihydroorotate and varied concentrations of 2,6-dichloroindophenol from 0-0.2 mM
0.042
dihydroorotate
full-length DHODH, fixed concentration of dihydroorotate of 1.0 mM and varied concentrations of decylubiquinone from 0-0.2 mM
0.065
dihydroorotate
N-terminally truncated DHODH, fixed concentration of dihydroorotate of 1.0 mM and varied concentrations of decylubiquinone from 0-0.2 mM
0.108
dihydroorotate
full-length DHODH, concentration of dihydroorotate varied from 0-1.0 mM at fixed concentrations of 0.1 mM decylubiquinone and 0.06 mM 2,6-dichloroindophenol
0.111
dihydroorotate
N-terminally truncated DHODH, concentration of dihydroorotate varied from 0-1.0 mM at fixed concentrations of 0.1 mM decylubiquinone and 0.06 mM 2,6-dichloroindophenol
0.122
dihydroorotate
full-length DHODH, fixed concentration of dihydroorotate of 1.0 mM and varied concentrations of 2,6-dichloroindophenol from 0-0.2 mM
0.015
L-dihydroorotate
pH 8.0, 25°C, cosubstrate Q6, N-terminally truncated protein
0.016
L-dihydroorotate
pH 8.0, 25°C, cosubstrate QD, N-terminally truncated protein
0.021
L-dihydroorotate
pH 8.0, 25°C, cosubstrate Q4, N-terminally truncated protein
0.056
L-dihydroorotate
pH 8.0, 25°C, cosubstrate vitamin K3, N-terminally truncated protein
0.114
L-dihydroorotate
pH 8.0, 25°C, cosubstrate Q0, N-terminally truncated protein
0.062
ubiquinone-6
pH 8.0, 25°C, cosubstrate L-dihydroorotate, N-terminally truncated protein
