1.3.3.6: acyl-CoA oxidase
This is an abbreviated version!
For detailed information about acyl-CoA oxidase, go to the full flat file.
Word Map on EC 1.3.3.6
-
1.3.3.6
-
beta-oxidation
-
proliferator-activated
-
ppars
-
carnitine
-
catalase
-
triglyceride
-
hepatocytes
-
cholesterol
-
pparalpha
-
thiolase
-
palmitoyltransferase
-
steatosis
-
adipose
-
proliferators
-
high-fat
-
sterol
-
clofibrate
-
hypolipidemic
-
enoyl-coa
-
3-ketoacyl-coa
-
adrenoleukodystrophy
-
ciprofibrate
-
zellweger
-
fenofibrate
-
refsum
-
bezafibrate
-
very-long-chain
-
perfluorooctanoic
-
cyp4a1
-
plasmalogens
-
pristanic
-
srebp-1c
-
3-hydroxyacyl-coa
-
phytanic
-
fibrates
-
cyanide-insensitive
-
rxralpha
-
vlcfas
-
nafenopin
-
lignoceric
-
medicine
-
pmp70
-
rhizomelic
-
3-oxoacyl-coa
-
nutrition
-
degradation
-
analysis
-
2,4-dienoyl-coa
-
omega-oxidation
-
biotechnology
-
di2-ethylhexylphthalate
-
clofibrate-treated
-
peroxisome-proliferator
-
l-fabp
-
peroxins
- 1.3.3.6
-
beta-oxidation
-
proliferator-activated
-
ppars
- carnitine
- catalase
- triglyceride
- hepatocytes
- cholesterol
- pparalpha
-
thiolase
- palmitoyltransferase
- steatosis
- adipose
- proliferators
-
high-fat
- sterol
- clofibrate
-
hypolipidemic
- enoyl-coa
- 3-ketoacyl-coa
- adrenoleukodystrophy
- ciprofibrate
- zellweger
- fenofibrate
- refsum
- bezafibrate
-
very-long-chain
-
perfluorooctanoic
- cyp4a1
- plasmalogens
-
pristanic
- srebp-1c
- 3-hydroxyacyl-coa
-
phytanic
-
fibrates
-
cyanide-insensitive
-
rxralpha
-
vlcfas
-
nafenopin
-
lignoceric
- medicine
- pmp70
-
rhizomelic
- 3-oxoacyl-coa
- nutrition
- degradation
- analysis
-
2,4-dienoyl-coa
-
omega-oxidation
- biotechnology
-
di2-ethylhexylphthalate
-
clofibrate-treated
-
peroxisome-proliferator
-
l-fabp
- peroxins
Reaction
Synonyms
3alpha,7alpha, 12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase, ACO, ACO I, ACO-A1, ACO-I, ACO-II, ACOX, ACOX-1, ACOX-1.1, ACOX-1.2, ACOX-1.3, ACOX-2, ACOX-3, ACOX1, ACOX1-3I, ACOX1a, ACOX1b, ACOX1–3II, ACOX2, ACOX3, ACX, ACX1, ACX1.2, ACX2, ACX3, ACX4, ACX5, acyl coenzyme A oxidase, acyl-CoA dehydrogenase, Acyl-CoA oxidase, acyl-CoA oxidase 1, acyl-CoA oxidase 1a, acyl-CoA oxidase 1b, acyl-CoA oxidase 2, acyl-CoA oxidase 4, acyl-CoA oxidase I, acyl-CoA oxidase-1, acyl-CoA oxidase-II, acyl-CoA-oxidase, acyl-coenzyme A oxidase, acyl-coenzyme A oxidase 1, acyl-coenzyme A oxidase 4, acyl-coenzyme A: oxygen oxidoreductase, AOX, AOX1, AOX2, Aox2p, AOX3, Aox3p, AOX4, aoxA, Aoxp, AtACX1, AtACX2, AtACX3, AtSACX, BRCACox, CrACX2, Cre05.g232002, fatty acyl-CoA oxidase, fatty acyl-coenzyme A oxidase, long chain acyl-CoA oxidase, long chain fatty acyl coenzyme A oxidase, long chain fatty acyl-CoA oxidase, long-chain-specific acyl-CoA oxidase 1, MCAD Y375K, MCOX, oxidase, acyl-coenzyme A, palmitoyl-CoA oxidase, peroxisomal acyl-coenzyme A oxidase, Peroxisomal fatty acyl-CoA oxidase, POX1, Pox1p, POX4, PpACX1, Pristanoyl-CoA oxidase, SCOX, short chain-specific acyl-CoA oxidase, short-chain acyl-CoA oxidase, straight chain acyl-CoA oxidase, straight-chain acyl-coenzyme A oxidase, THCA-CoA oxidase, THCCox, Trihydroxycoprostanoyl-CoA oxidase
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Reference on EC 1.3.3.6 - acyl-CoA oxidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rachubinski, R.A.; Fujiki, Y.; Lazarow, P.B.
Cloning of cDNA coding for peroxisomal acyl-CoA oxidase from the yeast Candida tropicalis pK233
Proc. Natl. Acad. Sci. USA
82
3973-3977
1985
Candida tropicalis
Osumi, T.; Ozasa, H.; Hashimoto, T.
Molecular cloning of cDNA for rat acyl-CoA oxidase
J. Biol. Chem.
259
2031-2034
1984
Rattus norvegicus
Hovik, R.; Osmundsen, H.
A kinetic investigation of the acyl-CoA oxidase reaction with the use of a novel spectrophotometric assay. Inhibition by acetyl-CoA, CoA and FMN
Biochem. J.
263
297-299
1989
Rattus norvegicus
Vamecq, J.; Schepers, L.; Parmentier, G.; Mannaerts, G.P.
Inhibition of peroxisomal fatty acyl-CoA oxidase by antimycin A
Biochem. J.
248
603-607
1987
Rattus norvegicus
Kawaguchi, A.; Tsubotani, S.; Seyama, Y.; Yamakawa, T.; Osumi, T.; Hashimoto, T.; Kikuchi, T.; Ando, M.; Okuda, S.
Stereochemistry of dehydrogenation catalyzed by Acyl-CoA oxidase
J. Biochem.
88
1481-1486
1980
Yarrowia lipolytica, Rattus norvegicus
Osumi, T.; Hashimoto, T.; Ui, N.
Purification and properties of acyl-CoA oxidase from rat liver
J. Biochem.
87
1735-1746
1980
Rattus norvegicus
Reubsaet, F.A.G.; Veerkamp, J.H.; Bukkens, S.G.F.; Trijbels, J.M.F.; Monnens, L.A.H.
Acyl-CoA oxidase activity and peroxisomal fatty acid oxidation in rat tissues
Biochim. Biophys. Acta
958
434-442
1988
Rattus norvegicus
Inestrosa, N.C.; Bronfman, M.; Leighton, F.
Purification of the peroxisomal fatty acyl-CoA oxidase from rat liver
Biochem. Biophys. Res. Commun.
95
7-12
1980
Rattus norvegicus
Osumi, T.; Hashimoto, T.
Acyl-CoA oxidase of rat liver: a new enzyme for fatty acid oxidation
Biochem. Biophys. Res. Commun.
83
479-485
1978
Rattus norvegicus
Suzuki, H.; Yamada, J.; Watanabe, T.; Suga, T.
Compartmentation of dicarboxylic acid beta-oxidation in rat liver: importance of peroxisomes in the metabolism of dicarboxylic acids
Biochim. Biophys. Acta
990
25-30
1989
Rattus norvegicus
Schepers, L.; Van Veldhoven, P.P.; Casteels, M.; Eyssen, H.J.; Mannaerts, G.P.
Presence of three acyl-CoA oxidases in rat liver peroxisomes. An inducible fatty acyl-CoA oxidase, a noninducible fatty acyl-CoA oxidase, and a noninducible trihydroxycoprostanoyl-CoA oxidase
J. Biol. Chem.
265
5242-5246
1990
Rattus norvegicus
Bronfman, M.; Inestrosa, N.C.; Nervi, F.O.; Leighton, F.
Acyl-CoA synthetase and the peroxisomal enzymes of beta-oxidation in human liver. Quantitative analysis of their subcellular localization
Biochem. J.
224
709-720
1984
Homo sapiens
Shimizu, S.; Yasui, K.; Tani, Y.; Yamada, H.
Acyl-CoA oxidase from Candida tropicalis
Biochem. Biophys. Res. Commun.
91
108-113
1979
Candida tropicalis
Jiang, Z.; Thorpe, C.
Acyl-CoA oxidase from Candida tropicalis
Biochemistry
22
3752-3758
1983
Candida tropicalis
Coudron, P.E.; Frerman, F.E.; Schowalter, D.B.
Chemical and catalytic properties of the peroxisomal acyl-coenzyme A oxidase from Candida tropicalis
Arch. Biochem. Biophys.
226
324-336
1983
Candida tropicalis
Ueda, M.; Yamanoi, K.; Morikawa, T.; Okada, H.; Tanaka, A.
Peroxisomal localization of enzymes related to fatty acid beta-oxidation in an n-alkane-grown yeast, Candida tropicalis
Agric. Biol. Chem.
49
1821-1828
1985
Candida tropicalis
-
Skoneczny, M.; Chelstowska, A.; Rytka, J.
Study of the coinduction by fatty acids of catalase A and acyl-CoA oxidase in standard and mutant Saccharomyces cerevisiae strains
Eur. J. Biochem.
174
297-302
1988
Saccharomyces cerevisiae
Hill, D.E.; Boulay, R.; Rogers, D.
Complete nucleotide sequence of the peroxisomal acyl CoA oxidase from the alkane-utilizing yeast Candida maltosa
Nucleic Acids Res.
16
365-366
1988
Candida maltosa
Nwosu, V.U.; Mackness, M.I.; Burdett, K.; Connock, M.J.
Mouse kidney peroxisomal fatty acyl-CoA oxidase chain length specificity
Biochem. Soc. Trans.
14
128
1986
Mus musculus
-
Gerhardt, B.
Substrate specificity of peroxisomal acyl-CoA oxidase
Phytochemistry
24
251-252
1985
Vigna radiata, Spinacia oleracea
-
Greene, R.V.; Gould, J.M.
Fatty acyl-coenzyme A oxidase activity and H2O2 production in Phanerochaete chrysosporium mycelia
Biochem. Biophys. Res. Commun.
118
437-443
1984
Phanerodontia chrysosporium
Kirsch, T.; Löffler, H.G.; Kindl, H.
Plant acyl-CoA oxidase. Purification, characterization, and monomeric apoprotein
J. Biol. Chem.
261
8570-8575
1986
Cucumis sativus
Sztajer, H.; Wagner, G.; Schmid, R.D.
Bacterial short-chain acyl-CoA oxidase: production, purification and characterization
Appl. Microbiol. Biotechnol.
39
708-713
1993
Glutamicibacter nicotianae
-
Small, G.M.; Karpichev, I.V.; Luo, Y.
Regulation of peroxisomal fatty acyl-CoA oxidase in the yeast Saccharomyces cerevisiae
Adv. Exp. Med. Biol.
422
157-166
1997
Saccharomyces cerevisiae
Hayashi, H.; De Bellis, L.; Yamaguchi, K.; Kato, A.; Hayashi, M.; Nishimura, M.
Molecular characterization of a glyoxysomal long chain acyl-CoA oxidase that is synthesized as a precursor of higher molecular mass in pumpkin
J. Biol. Chem.
273
8301-8307
1998
Cucurbita sp.
Chu, R.; Varanasi, U.; Chu, S.; Lin, Y.; Usuda, N.; Rao, M.S.; Reddy, J.K.
Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells
J. Biol. Chem.
270
4908-4915
1995
Homo sapiens
Agarwal, A.K.; Qi, Y.; Bhat, D.G.; Woerner, B.M.; Brown, S.M.
Gene isolation and characterization of two acyl CoA oxidases from soybean with broad substrate specificities and enhanced expression in the growing seedling axis
Plant Mol. Biol.
47
519-531
2001
Glycine max
Froman, B.E.; Edwards, P.C.; Bursch, A.G.; Dehesh, K.
ACX3, a novel medium-chain acyl-coenzyme A oxidase from Arabidopsis
Plant Physiol.
123
733-741
2000
Brassica napus, Arabidopsis thaliana (P0CZ23)
Luo, Y.S.; Wang, H.J.; Gopalan, K.V.; Srivastava, D.K.; Nicaud, J.M.; Chardot, T.
Purification and characterization of the recombinant form of acyl CoA oxidase 3 from the yeast Yarrowia lipolytica
Arch. Biochem. Biophys.
384
1-8
2000
Yarrowia lipolytica
Nakajima, Y.; Miyahara, I.; Hirotsu, K.; Nishina, Y.; Shiga, K.; Setoyama, C.; Tamaoki, H.; Miura, R.
Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase
J. Biochem.
131
365-374
2002
Rattus norvegicus
Tamaoki, H.; Setoyama, C.; Miura, R.; Hazekawa, I.; Nishina, Y.; Shiga, K.
Spectroscopic studies of rat liver acyl-CoA oxidase with reference to recognition and activation of substrate
J. Biochem.
121
1139-1146
1997
Rattus norvegicus
Hooks, M.A.; Bode, K.; Couee, I.
Higher-plant medium- and short-chain acyl-CoA oxidases: identification, purification and characterization of two novel enzymes of eukaryotic peroxisomal.beta-oxidation
Biochem. J.
320
607-614
1996
Zea mays
Hooks, M.A.; Kellas, F.; Graham, I.A.
Long-chain acyl-CoA oxidases of Arabidopsis
Plant J.
20
1-13
1999
Arabidopsis thaliana
Chu, C.; Mao, L.F.; Schulz, H.
Estimation of peroxisomal.beta-oxidation in rat heart by a direct assay of acyl-CoA oxidase
Biochem. J.
302
23-29
1994
Rattus norvegicus
-
Nohammer, C.; El-Shabrawi, Y.; Schauer, S.; Hiden, M.; Berger, J.; Forss-Petter, S.; Winter, E.; Eferl, R.; Zechner, R.; Hoefler, G.
cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase
Eur. J. Biochem.
267
1254-1260
2000
Mus musculus
Pedersen, L.; Henriksen, A.
Expression, purification and crystallization of two peroxisomal acyl-CoA oxidases from Arabidopsis thaliana
Acta Crystallogr. Sect. D
60
1125-1128
2004
Arabidopsis thaliana (O65202), Arabidopsis thaliana
Mlickova, K.; Roux, E.; Athenstaedt, K.; d'Andrea, S.; Daum, G.; Chardot, T.; Nicaud, J.M.
Lipid accumulation, lipid body formation, and acyl coenzyme A oxidases of the yeast Yarrowia lipolytica
Appl. Environ. Microbiol.
70
3918-3924
2004
Yarrowia lipolytica
Luo, Y.S.; Nicaud, J.M.; Van Veldhoven, P.P.; Chardot, T.
The acyl-CoA oxidases from the yeast Yarrowia lipolytica: characterization of Aox2p
Arch. Biochem. Biophys.
407
32-38
2002
Yarrowia lipolytica (O74935), Yarrowia lipolytica
Ngo, S.N.; McKinnon, R.A.; Stupans, I.
The effects of Eucalyptus terpenes on hepatic cytochrome P450 CYP4A, peroxisomal acyl CoA oxidase (AOX) and peroxisome proliferator activated receptor alpha (PPARalpha) in the common brush tail possum (Trichosurus vulpecula)
Comp. Biochem. Physiol. C
136
165-173
2003
Trichosurus vulpecula
Ngo, S.N.; McKinnon, R.A.; Stupans, I.
Identification and cloning of two forms of liver peroxisomal fatty acyl CoA oxidase from the koala (Phascolarctos cinereus)
Gene
309
91-99
2003
Phascolarctos cinereus (Q8HYL8), Phascolarctos cinereus
Klein, A.T.; van den Berg, M.; Bottger, G.; Tabak, H.F.; Distel, B.
Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p
J. Biol. Chem.
277
25011-25019
2002
Saccharomyces cerevisiae
Pedersen, L.; Henriksen, A.
Acyl-CoA oxidase 1 from Arabidopsis thaliana. Structure of a key enzyme in plant lipid metabolism
J. Mol. Biol.
345
487-500
2005
Arabidopsis thaliana
Grossi, M.; Giuntini, P.; Mazzucotelli, E.; Crosatti, C.; Pisteli, L.; De Bellis, L.; Alpi, A.; Stanca, A.M.; Cattivelli, L.
Cloning and characterization of barley long chain acyl-CoA oxidase and its possible regulation by glucose
Physiol. Plant.
117
22-32
2003
Hordeum vulgare
-
Ding, S.T.; Li, Y.C.; Nestor, K.E.; Velleman, S.G.; Mersmann, H.J.
Expression of turkey transcription factors and acyl-coenzyme oxidase in different tissues and genetic populations
Poult. Sci.
82
17-24
2003
Meleagris gallopavo
Zeng, J.; Li, D.
Expression and purification of his-tagged rat peroxisomal acyl-CoA oxidase I wild-type and E421 mutant proteins
Protein Expr. Purif.
38
153-160
2004
Rattus norvegicus
Powers, R.A.; Rife, C.L.; Schilmiller, A.L.; Howe, G.A.; Garavito, R.M.
Structure determination and analysis of acyl-CoA oxidase (ACX1) from tomato
Acta Crystallogr. Sect. D
D62
683-686
2006
Solanum lycopersicum
Coulter, A.A.; Stephens, J.M.
STAT5 activators modulate acyl CoA oxidase (AOX) expression in adipocytes and STAT5A binds to the AOX promoter in vitro
Biochem. Biophys. Res. Commun.
344
1342-1345
2006
Mus musculus
Zeng, J.; Deng, G.; Li, D.
Intrinsic enoyl-CoA isomerase activity of rat acyl-CoA oxidase I
Biochim. Biophys. Acta
1760
78-85
2006
Rattus norvegicus
Bakke, M.; Setoyama, C.; Miura, R.; Kajiyama, N.
N-Ethylmaleimide-resistant acyl-coenzyme A oxidase from Arthrobacter ureafaciens NBRC 12140: Molecular cloning, gene expression and characterization of the recombinant enzyme
Biochim. Biophys. Acta
1774
65-71
2007
Candida sp. (in: Saccharomycetales), Paenarthrobacter ureafaciens (Q33DR0), Paenarthrobacter ureafaciens, Arthrobacter sp. (Q33DR1), Paenarthrobacter ureafaciens NBRC 12140 (Q33DR0), Arthrobacter sp. 02.04.2001 (Q33DR1)
Oakes, K.D.; Sibley, P.K.; Martin, J.W.; MacLean, D.D.; Solomon, K.R.; Mabury, S.A.; Van Der Kraak, G.J.
Short-term exposures of fish to perfluorooctane sulfonate: acute effects on fatty acyl-coa oxidase activity, oxidative stress, and circulating sex steroids
Environ. Toxicol. Chem.
24
1172-1181
2005
Oncorhynchus mykiss, Pimephales promelas, Semotilus atromaculatus, Notropis hudsonius, Catostomus commersonii
Feron, G.; Blin-Perrin, C.; Krasniewski, I.; Mauvais, G.; Lherminier, J.
Metabolism of fatty acid in yeast: characterisation of beta-oxidation and ultrastructural changes in the genus Sporidiobolus sp. cultivated on ricinoleic acid methyl ester
FEMS Microbiol. Lett.
250
63-69
2005
Rhodosporidiobolus ruineniae, no activity in Sporidiobolus pararoseus, Rhodosporidiobolus ruineniae CBS5001, no activity in Sporidiobolus pararoseus CBS484
Findley, A.M.; Weidner, E.H.; Carman, K.R.; Xu, Z.; Godbar, J.S.
Role of the posterior vacuole in Spraguea lophii (Microsporidia) spore hatching
Folia Parasitol.
52
111-117
2005
Spraguea lophii
Alconada, T.M.; Juarez, M.P.
Acyl-CoA oxidase activity from Beauveria bassiana, an entomopathogenic fungus
J. Basic Microbiol.
46
435-443
2006
Beauveria bassiana, Beauveria bassiana GHA
Ito, R.; Morita, M.; Takahashi, N.; Shimozawa, N.; Usuda, N.; Imanaka, T.; Ito, M.
Identification of Pex5pM, and retarded maturation of 3-ketoacyl-CoA thiolase and acyl-CoA Oxidase in CHO cells expressing mutant Pex5p isoforms
J. Biochem.
138
781-790
2005
Cricetulus griseus
Tokuoka, K.; Nakajima, Y.; Hirotsu, K.; Miyahara, I.; Nishina, Y.; Shiga, K.; Tamaoki, H.; Setoyama, C.; Tojo, H.; Miura, R.
Three-dimensional structure of rat-liver acyl-CoA oxidase in complex with a fatty acid: insights into substrate-recognition and reactivity toward molecular oxygen
J. Biochem.
139
789-795
2006
Rattus norvegicus (P07872)
Mackenzie, J.; Pedersen, L.; Arent, S.; Henriksen, A.
Controlling electron transfer in acyl-CoA oxidases and dehydrogenases
J. Biol. Chem.
281
31012-31020
2006
Arabidopsis thaliana (Q96329), Arabidopsis thaliana
Kim, M.C.; Kim, T.H.; Park, J.H.; Moon, B.Y.; Lee, C.H.; Cho, S.H.
Expression of rice acyl-CoA oxidase isoenzymes in response to wounding
J. Plant Physiol.
164
665-668
2007
Oryza sativa, Oryza sativa (Q5VRH3), Oryza sativa (Q69XR7)
Kim, H.K.; Choi, H.
Stimulation of acyl-CoA oxidase by alpha-linolenic acid-rich perilla oil lowers plasma triacylglycerol level in rats
Life Sci.
77
1293-1306
2005
Rattus norvegicus
Morais, S.; Knoll-Gellida, A.; Andre, M.; Barthe, C.; Babin, P.J.
Conserved expression of alternative splicing variants of peroxisomal acyl-CoA oxidase 1 in vertebrates and developmental and nutritional regulation in fish
Physiol. Genomics
28
239-252
2007
Danio rerio, Danio rerio (Q4QRE2), Oncorhynchus mykiss
Adham, A.R.; Zolman, B.K.; Millius, A.; Bartel, B.
Mutations in Arabidopsis acyl-CoA oxidase genes reveal distinct and overlapping roles in beta-oxidation
Plant J.
41
859-874
2005
Arabidopsis thaliana
Pinfield-Wells, H.; Rylott, E.L.; Gilday, A.D.; Graham, S.; Job, K.; Larson, T.R.; Graham, I.A.
Sucrose rescues seedling establishment but not germination of Arabidopsis mutants disrupted in peroxisomal fatty acid catabolism
Plant J.
43
861-872
2005
Arabidopsis thaliana (O65201), Arabidopsis thaliana (O65202), Arabidopsis thaliana (P0CZ23), Arabidopsis thaliana (Q96329)
Carrozzo, R.; Bellini, C.; Lucioli, S.; Deodato, F.; Cassandrini, D.; Cassanello, M.; Caruso, U.; Rizzo, C.; Rizza, T.; Napolitano, M.L.; Wanders, R.J.; Jakobs, C.; Bruno, C.; Santorelli, F.M.; Dionisi-Vici, C.; Bonioli, E.
Peroxisomal acyl-CoA-oxidase deficiency: two new cases
Am. J. Med. Genet. A
146A
1676-1681
2008
Homo sapiens (Q15067), Homo sapiens
Oaxaca-Castillo, D.; Andreoletti, P.; Vluggens, A.; Yu, S.; van Veldhoven, P.P.; Reddy, J.K.; Cherkaoui-Malki, M.
Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene
Biochem. Biophys. Res. Commun.
360
314-319
2007
Homo sapiens
Zeng, J.; Liu, Y.; Wu, L.; Li, D.
Mutation of Tyr375 to Lys375 allows medium-chain acyl-CoA dehydrogenase to acquire acyl-CoA oxidase activity
Biochim. Biophys. Acta
1774
1628-1634
2007
Rattus norvegicus
Garcia, E.E.; Nicaud, J.M.; Belin, J.M.; Wache, Y.
Effect of acyl-CoA oxidase activity on the accumulation of gamma-decalactone by the yeast Yarrowia lipolytica: a factorial approach
Biotechnol. J.
2
1280-1285
2007
Yarrowia lipolytica, Yarrowia lipolytica W29 / ATCC 20460
Ceci, R.; Sabatini, S.; Duranti, G.; Savini, I.; Avigliano, L.; Rossi, A.
Acute, but not chronic, leptin treatment induces acyl-CoA oxidase in C2C12 myotubes
Eur. J. Nutr.
46
364-368
2007
Mus musculus
Zolman, B.K.; Nyberg, M.; Bartel, B.
IBR3, a novel peroxisomal acyl-CoA dehydrogenase-like protein required for indole-3-butyric acid response
Plant Mol. Biol.
64
59-72
2007
Arabidopsis thaliana
Arent, S.; Pye, V.E.; Henriksen, A.
Structure and function of plant acyl-CoA oxidases
Plant Physiol. Biochem.
46
292-301
2008
Arabidopsis thaliana (O65201), Arabidopsis thaliana (O65202), Arabidopsis thaliana (P0CZ23), Arabidopsis thaliana (Q96329), Arabidopsis thaliana (Q9ZQP2)
Sode, K.; Tsugawa, W.; Aoyagi, M.; Rajashekhara, E.; Watanabe, K.
Propionate sensor using coenzyme-A transferase and acyl-CoA oxidase
Protein Pept. Lett.
15
779-781
2008
Arabidopsis thaliana
Zeng, J.; Wu, L.; Zhang, X.; Liu, Y.; Deng, G.; Li, D.
Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase
Org. Lett.
10
4287-4290
2008
Rattus norvegicus
Ferdinandusse, S.; Barker, S.; Lachlan, K.; Duran, M.; Waterham, H.; Wanders, R.; Hammans, S.
Adult peroxisomal acyl-coenzyme A oxidase deficiency with cerebellar and brainstem atrophy
J. Neurol. Neurosurg. Psychiatry
81
310-312
2010
Homo sapiens
Vluggens, A.; Andreoletti, P.; Viswakarma, N.; Jia, Y.; Matsumoto, K.; Kulik, W.; Khan, M.; Huang, J.; Guo, D.; Yu, S.; Sarkar, J.; Singh, I.; Rao, M.S.; Wanders, R.J.; Reddy, J.K.; Cherkaoui-Malki, M.
Reversal of mouse acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]
Lab. Invest.
90
696-708
2010
Homo sapiens, Mus musculus
Reiser, K.; Davis, M.A.; Hynes, M.J.
AoxA is a major peroxisomal long chain fatty acyl-CoA oxidase required for beta-oxidation in A. nidulans
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Aspergillus nidulans
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Roles of multiple acyl-CoA oxidases in the routing of carbon flow towards beta-oxidation and polyhydroxyalkanoate biosynthesis in Yarrowia lipolytica
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Yarrowia lipolytica, Yarrowia lipolytica W29 / ATCC 20460
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Peroxisomal Acyl-CoA oxidase 4 activity differs between Arabidopsis accessions
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Arabidopsis thaliana, Arabidopsis thaliana Col-0
Zeng, J.; Deng, S.; Wang, Y.; Li, P.; Tang, L.; Pang, Y.
Specific inhibition of acyl-CoA oxidase-1 by an acetylenic acid improves hepatic lipid and reactive oxygen species (ROS) metabolism in rats fed a high fat diet
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Rattus norvegicus (P07872)
Zhang, L.; Li, H.; Gao, L.; Qi, Y.; Fu, W.; Li, X.; Zhou, X.; Gao, Q.; Gao, Z.; Jia, H.
Acyl-CoA oxidase 1 is involved in gamma-decalactone release from peach (Prunus persica) fruit
Plant Cell Rep.
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Prunus persica (J7K6M3), Prunus persica
Kong, F.; Liang, Y.; Legeret, B.; Beyly-Adriano, A.; Blangy, S.; Haslam, R.P.; Napier, J.A.; Beisson, F.; Peltier, G.; Li-Beisson, Y.
Chlamydomonas carries out fatty acid beta-oxidation in ancestral peroxisomes using a bona fide acyl-CoA oxidase
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Chlamydomonas reinhardtii (A8J3M3), Chlamydomonas reinhardtii
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Acyl-CoA oxidase complexes control the chemical message produced by Caenorhabditis elegans
Proc. Natl. Acad. Sci. USA
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Caenorhabditis elegans (O62137), Caenorhabditis elegans (O62138), Caenorhabditis elegans (O62140), Caenorhabditis elegans, Caenorhabditis elegans N2 (O62138)
Deng, S.; Li, P.; Wang, Y.; Zeng, J.
tyrosine residues 232 and 401 play a critical role in the binding of the cofactor FAD of acyl-CoA oxidase
Appl. Biochem. Biotechnol.
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2018
Rattus norvegicus (P07872)
Kim, S.; Kim, K.J.
Structural insight into the substrate specificity of acyl-CoA oxidase1 from Yarrowia lipolytica for short-chain dicarboxylyl-CoAs
Biochem. Biophys. Res. Commun.
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2018
Yarrowia lipolytica (O74934), Yarrowia lipolytica, Yarrowia lipolytica CLIB 122 (O74934)
Ferdinandusse, S.; Denis, S.; van Roermund, C.W.T.; Preece, M.A.; Koster, J.; Ebberink, M.S.; Waterham, H.R.; Wanders, R.J.A.
A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase
Biochim. Biophys. Acta Mol. Basis Dis.
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2018
Homo sapiens (O15254), Homo sapiens (Q15067), Homo sapiens (Q99424), Homo sapiens
Ju, J.H.; Oh, B.R.; Heo, S.Y.; Lee, Y.U.; Shon, J.H.; Kim, C.H.; Kim, Y.M.; Seo, J.W.; Hong, W.K.
Production of adipic acid by short- and long-chain fatty acid acyl-CoA oxidase engineered in yeast Candida tropicalis
Bioprocess Biosyst. Eng.
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Candida tropicalis (P06598), Candida tropicalis, Candida tropicalis KCTC 7212 (P06598)
Kempinski, B.; Chelstowska, A.; Poznanski, J.; Krol, K.; Rymer, L.; Frydzinska, Z.; Girzalsky, W.; Skoneczna, A.; Erdmann, R.; Skoneczny, M.
The peroxisomal targeting signal 3 (PTS3) of the budding yeast acyl-CoA oxidase is a signal patch
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Saccharomyces cerevisiae
Okamura, M.; Ueno, T.; Tanaka, S.; Murata, Y.; Kobayashi, H.; Miyamoto, A.; Abe, M.; Fukuda, N.
Increased expression of acyl-CoA oxidase 2 in the kidney with plasma phytanic acid and altered gut microbiota in spontaneously hypertensive rats
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2021
Rattus norvegicus
Kim, S.; Kim, K.J.
Crystal structure of acyl-CoA oxidase 3 from Yarrowia lipolytica with specificity for short-chain acyl-CoA
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2018
Yarrowia lipolytica (O74936), Yarrowia lipolytica CLIB 122 (O74936)
Xin, Z.; Chen, S.; Ge, L.; Li, X.; Sun, X.
The involvement of a herbivore-induced acyl-CoA oxidase gene, CsACX1, in the synthesis of jasmonic acid and its expression in flower opening in tea plant (Camellia sinensis)
Plant Physiol. Biochem.
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2019
Camellia sinensis (A0A222YU64), Camellia sinensis
Shi, H.; Huang, X.; Chen, X.; Yang, Y.; Wang, Z.; Yang, Y.; Wu, F.; Zhou, J.; Yao, C.; Ma, G.; Du, A.
Acyl-CoA oxidase ACOX-1 interacts with a peroxin PEX-5 to play roles in larval development of Haemonchus contortus
PLoS Pathog.
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2021
Haemonchus contortus, Haemonchus contortus ZJ
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