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1.3.3.4: protoporphyrinogen oxidase

This is an abbreviated version!
For detailed information about protoporphyrinogen oxidase, go to the full flat file.

Word Map on EC 1.3.3.4

Reaction

protoporphyrinogen IX
+ 3 O2 =
protoporphyrin IX
 + 3 H2O2

Synonyms

HemG, HemG-type PPO, HemG-type protoporphyrinogen IX oxidase, hemY, hPPO, H_N10, H_N40, H_N90, LMJF_06_1280, mtPPO, MxPPOX, MxProtox, PPO, PPO1, ppo1-1, PPO2, PPOX, PPOX I, PPX1, PPX2, protein YfeX, protogen oxidase, protoporphyrinogen IX oxidase, protoporphyrinogen IX oxidase 1, protoporphyrinogen oxidase, protoporphyrinogen oxidase IX, protoporphyrinogenase, protox, Protox enzyme, R-PPO, Rs-slr1790 protein, S-PPO, Salk_143057, YfeX

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.4 protoporphyrinogen oxidase

Temperature Stability

Temperature Stability on EC 1.3.3.4 - protoporphyrinogen oxidase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
45
-
inactivated above 45°C, half maximal activity after 100 min
47.6
-
50% inactivation of mutant R168C
50.2
-
50% inactivation of mutant Y348C
53
-
50% inactivation of mutant R59W
54.2
-
50% inactivation of mutant R59I
55
-
60 min at 55°C causes 80% loss of activity
56.3
-
50% inactivation of mutant R59K
56.8
-
50% inactivation of recombinant wild-type enzyme
57
-
50% inactivation of mutant G14A
60.3
-
50% inactivation of mutant R59S