1.3.1.B7: (3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate reductase [NAD(P)H] This is an abbreviated version! For detailed information about (3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate reductase [NAD(P)H], go to the full flat file .
Reaction
3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate +
NAD(P)+ =
3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate +
NAD(P)H +
H+
Synonyms BacG, YwfH
ECTree
Engineering
Engineering on EC 1.3.1.B7 - (3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate reductase [NAD(P)H]
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K113A
-
kcat/Km is 4.9fold lower than the wild-type value
N158A
-
kcat/Km is 4.6fold lower than the wild-type value
S155A
-
kcat/Km is 5.5fold lower than the wild-type value
S250A
-
kcat/Km is 2.2fold lower than the wild-type value
Y117A
-
kcat/Km is 5.8fold lower than the wild-type value