1.3.1.90: tRNA-dihydrouridine20a/20b synthase [NAD(P)+]

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For detailed information about tRNA-dihydrouridine20a/20b synthase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

Dus4p, tRNA-dihydrouridine synthase 4

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]

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4	AA Sequence
1	General Information
2	Natural Substrates/ Products (Substrates)
1	Organism
4	Reaction
1	Reference
4	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name

General Information

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General Information on EC 1.3.1.90 - tRNA-dihydrouridine20a/20b synthase [NAD(P)+]

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

physiological function

Saccharomyces cerevisiae

Q06063

formation of dihydrouridine in yeast cytoplasmic tRNAs is carried out by a family of four dihydrouridine synthases (Dus1p, Dus2p, Dus3p, and Dus4p), each acting at specific positions in tRNAs. Dus1p modifies U16 and U17, Dus2p modifies U20, Dus3p modifies U47, and Dus4p modifies U20a and U20b. These four proteins are responsible for all dihydrouridine modification of cytoplasmic tRNAs in yeast

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