1.3.1.78: arogenate dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about arogenate dehydrogenase (NADP+), go to the full flat file.
Word Map on EC 1.3.1.78
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1.3.1.78
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kinase-inactive
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prephenate
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gadd45
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malformation
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annexin
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ifngamma
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neurulation
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perinuclear
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calcium-dependent
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mekks
- 1.3.1.78
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kinase-inactive
- prephenate
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gadd45
-
malformation
-
annexin
-
ifngamma
-
neurulation
-
perinuclear
-
calcium-dependent
-
mekks
Reaction
Synonyms
ADH1, ADH2, arogenate dehydrogenase, arogenate dehydrogenase isoform 1, arogenate dehydrogenase isoform 2, cyclohexadienyl dehydrogenase, TyrA arogenate dehydrogenase, TyrA1, TyrA2, TyrAa, TyrAAT, TyrAAT1, TyrAsy
ECTree
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Substrates Products
Substrates Products on EC 1.3.1.78 - arogenate dehydrogenase (NADP+)
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REACTION DIAGRAM
prephenate + NADP+
3-(4-hydroxyphenyl)-2-oxopropanoate + CO2 + NADPH
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-
-
-
?
L-arogenate + NAD(P)+
L-tyrosine + NAD(P)H + CO2
-
-
-
?
L-arogenate + NAD+
L-tyrosine + NADH + CO2
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exclusive metabolic route to tyrosine
-
?
L-arogenate + NAD+
L-tyrosine + NADH + CO2
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i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine
-
?
L-arogenate + NAD+
L-tyrosine + NADH + CO2
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important enzyme in regulation of tyrosine biosynthesis
-
?
L-arogenate + NAD+
L-tyrosine + NADH + CO2
-
i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine
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?
L-tyrosine + NADPH + CO2
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enzyme of the arogenate pathway
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-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
rapid equilibrium random mechanism in which two dead-end complexes, enzyme-NADPH-arogenate and enzyme-NADP+-tyrosine are formed
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-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
specific for, no activity with prephenate and NAD+
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
enzyme of the arogenate pathway
-
-
?
L-arogenate + NADP+
L-tyrosine + NADPH + CO2
-
specific for, no activity with prephenate and NAD+
-
-
?
additional information
?
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-
TyrAAT1 is four times more efficient in catalyzing arogenate dehydrogenase reaction than TyrAAT2. TyrAAT2 presents a weak prephenate dehydrogenase activity whereas Tyr-AAT1 does not
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-
?
additional information
?
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-
no activity with prephenate and NAD+
-
-
?
additional information
?
-
-
no activity with prephenate and NAD+
-
-
?
additional information
?
-
-
no activity with prephenate and NAD+
-
-
?
additional information
?
-
-
no activity with prephenate and NAD+
-
-
?
additional information
?
-
no activity with prephenate and NAD+
-
-
?
additional information
?
-
-
no activity with prephenate and NAD+
-
-
?