1.3.1.76: precorrin-2 dehydrogenase

This is an abbreviated version!
For detailed information about precorrin-2 dehydrogenase, go to the full flat file.

Reaction

Synonyms

cobaltochelatase, CysG, CysG enzyme, cysG gene product, CysG2, EC 2.1.1.107, Met8p, P2D, precorrin-2 dehydrogenase, S-adenosyl-L-methionine(SAM)-dependent bismethyltransferase, dehydrogenase and ferrochelatase, SirC, siroheme synthase, siroheme synthetase

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.76 precorrin-2 dehydrogenase

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Results	in table
20904	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
5	Cofactor
4	Crystallization (Commentary)
1	KM Value [mM]
2	Metals/Ions
6	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
15	Organism
11	Pathway
24	PDB ID
1	Posttranslational Modification
12	Protein Variants
7	Purification (Commentary)
2	Reaction
3	Reaction Type
14	Reference
7	Specific Activity [micromol/min/mg]
26	Substrates and Products (Substrate)
8	Subunits
31	Synonyms
1	Systematic Name

Crystallization

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Crystallization on EC 1.3.1.76 - precorrin-2 dehydrogenase

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CRYSTALLIZATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

hanging drop vapour diffusion method

Priestia megaterium

P61818

685013

space group C2, a : 156.1 A,b : 81.2 A, c : 104.2 A

Saccharomyces cerevisiae

P15807

644283

orthorhombic space group P2(1)2(1)2(1), unit cell dimensions a = 60.73 A, b = 121.49 A, c = 130.79 A

Salmonella enterica

-

653297

S128A mutant enzyme bound to precorrin-2, sirohydrochlorin, and a cobalt-sirohydrochlorin product, hanging drop vapor diffusion method, using 100 mM MES pH 5.0, 500 mM NaCl, 1% (v/v) 2-mercaptoethanol and 10-20% (w/v) PEG4000

Salmonella enterica subsp. enterica serovar Typhimurium

P25924

765450