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1.3.1.7: meso-tartrate dehydrogenase

This is an abbreviated version!
For detailed information about meso-tartrate dehydrogenase, go to the full flat file.

Reaction

meso-tartrate
+
NAD+
=
Dihydroxyfumarate
+
NADH
+
H+

Synonyms

tartrate dehydrogenase, TDH

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.7 meso-tartrate dehydrogenase

Substrates Products

Substrates Products on EC 1.3.1.7 - meso-tartrate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,3R)-3-bromomalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3R)-3-chloromalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3R)-3-fluoromalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3R)-3-iodomalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3R)-3-methyltartrate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3R)-3-thiomalate + NAD+
?
show the reaction diagram
-
-
-
-
?
(2R,3S)-3-bromomalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3S)-3-chloromalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3S)-3-fluoromalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3S)-3-iodomalate + NAD+
? + CO2 + NADH
show the reaction diagram
-
oxidative decarboxylation
-
-
?
(2R,3S)-3-methyltartrate + NAD+
? + NADH
show the reaction diagram
-
simple oxidation
-
-
?
(2R,3S)-3-thiomalate + NAD+
?
show the reaction diagram
-
net non-oxidative decarboxylation
-
-
?
D-malate + 3-acetylpyridine adenine dinucleotide
pyruvate + CO2 + reduced 3-acetylpyridine adenine dinucleotide
show the reaction diagram
-
-
-
-
r
D-malate + 3-pyridinealdehyde adenine dinucleotide
pyruvate + CO2 + reduced 3-pyridinealdehyde adenine dinucleotide
show the reaction diagram
-
-
-
-
r
D-malate + NAD+
pyruvate + CO2 + NADH
show the reaction diagram
-
-
-
-
r
D-malate + NAD+
pyruvate + CO2 + NADH + H+
show the reaction diagram
-
-
-
-
r
D-malate + thio-NAD+
pyruvate + CO2 + thio-NADH
show the reaction diagram
-
-
-
-
r
dihydroxyfumaric acid + NADH
meso-tartrate + NAD+
show the reaction diagram
-
-
-
-
r
L-(+)-tartrate + NAD+
(3R)-oxaloglycolate + NADH
show the reaction diagram
malate + NAD+
pyruvate + CO2 + NADH + H+
show the reaction diagram
meso-tartrate + 3-acetylpyridine-NAD+
D-glycerate + CO2 + ?
show the reaction diagram
-
3-acetylpyridine-NAD+ is a very slow substrate for TDH
-
?
meso-tartrate + NAD+
D-glycerate + CO2 + NADH + H+
show the reaction diagram
meso-tartrate + NAD+
dihydroxyfumaric acid + NADH + H+
show the reaction diagram
meso-tartrate + NAD+
oxaloglycolate + NADH + H+
show the reaction diagram
additional information
?
-
-
3R-oxaloglycolate, (2R,3S)-3-aminomalate and (2R,3R)-3-aminomalate are no substrates
-
-
?