1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)
This is an abbreviated version!
For detailed information about trans-2-enoyl-CoA reductase (NADPH), go to the full flat file.
Word Map on EC 1.3.1.38
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1.3.1.38
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beta-ketoacyl-coa
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beta-hydroxyacyl-coa
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dehydrase
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palmitoyl-coa
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butyryl-coa
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condensing
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vlcfas
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nadph-specific
- 1.3.1.38
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beta-ketoacyl-coa
-
beta-hydroxyacyl-coa
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dehydrase
- palmitoyl-coa
- butyryl-coa
-
condensing
-
vlcfas
-
nadph-specific
Reaction
Synonyms
2-trans enoyl-ACP(CoA) reductase, ECR, EgTER1, enoyl reductase, InhA, MECR, MECR-1, mitochondrial 2-trans-enoyl-CoA/ACP reductase, mitochondrial 2-trans-enoyl-thioester reductase, NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, TER, trans-2-enoyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH)
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General Information
General Information on EC 1.3.1.38 - trans-2-enoyl-CoA reductase (NADPH)
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malfunction
metabolism
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the enzyme is involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of sphingosine in sphingolipids through the sphingosine 1-phosphate metabolic pathway
physiological function
knockdown of MECR-1 resulted in life span extension
malfunction
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functional analysis of PaECR1 is conducted by virus-induced gene silencing to knock down the gene expression in Phalaenopsis amabilis. The PaECR1-silenced plants are more susceptible to Erwinia chrysanthemi infection, implying potential roles for very long chain fatty acids in the pathogenesis
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up-regulated expression upon Erwinia chrysanthemi infection
physiological function
the enzyme (EgTER1) is involved in the greening process. It is dispensable for wax ester production under anaerobic conditions