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1.3.1.34: 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing], go to the full flat file.

Word Map on EC 1.3.1.34

Reaction

a (2E)-2-enoyl-CoA
+
NADP+
=
a (2E,4E)-2,4-dienoyl-CoA
 +
NADPH
 +
H+

Synonyms

2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase (NADPH), 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase (NADPH), 4-enoyl-CoA reductase [NADPH], DCR, DECR, FADH, pDCR, peroxisomal 2,4-dienoyl CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

Substrates Products

Substrates Products on EC 1.3.1.34 - 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2E,4E)-2,4-decadienoyl-CoA + NADPH
?
show the reaction diagram
-
-
-
?
(2E,4E)-2,4-decadienoyl-CoA + NADPH + H+
(2E)-2-decaenoyl-CoA + NADP+
show the reaction diagram
-
-
-
-
?
(2E,4E)-2,4-hexadienoyl-CoA + NADPH
?
show the reaction diagram
-
-
-
?
2,4,7,10,13,16,19-docosaheptaenoyl-CoA + NADPH
?
show the reaction diagram
-
-
-
?
2,4-cis-tetradecadienoyl-CoA + NADPH
2-cis-dehydroacyl-CoA + NADP+
show the reaction diagram
-
low activity
-
-
?
2,4-hexadienoyl-CoA + NADPH
trans-3-hexenoyl-CoA + NADP+
show the reaction diagram
2,4-trans-decadienoyl-CoA + NADPH
? + NADP+
show the reaction diagram
2,4-trans-hexadienoyl-CoA + NADPH
trans-3-hexenoyl-CoA + NADP+
show the reaction diagram
-
-
-
-
?
2,4-trans-tetradecadienoyl-CoA + NADPH
2-trans-dehydroacyl-CoA + NADP+
show the reaction diagram
-
-
-
-
?
2-trans,4-cis-decadienoyl-CoA + NADPH
2-decenoyl-CoA + NADP+
show the reaction diagram
-
-
initial reaction product
?
2-trans,4-cis-decadienoyl-CoA + NADPH
3-trans-decenoyl-CoA + NADP+
show the reaction diagram
-
-
-
-
?
2-trans,4-trans-decadienoyl-CoA + NADPH
2-trans-decenoyl-CoA + NADP+
show the reaction diagram
2-trans,4-trans-decadienoyl-CoA + NADPH
3-decenoyl-CoA + NADP+
show the reaction diagram
2-trans,4-trans-decadienoyl-CoA + NADPH
3-trans-decenoyl-CoA + NADP+
show the reaction diagram
-
3-trans-decenoyl-CoA is the product of the mutant enzymes Y166F, H252A, and H252A/Y166F
-
?
2-trans,4-trans-hexadienoyl-CoA + NADPH
?
show the reaction diagram
5-phenyl-2,4-pentadienoyl-CoA + NADPH
?
show the reaction diagram
-
-
-
-
?
trans-trans-2,4-hexadecadienoyl-CoA + NADPH
trans-2-hexadecenoyl-CoA + NADP+
show the reaction diagram
-
step in the beta-oxidation of oleoyl-CoA via 2-trans-5-cis-tetradecadienoyl-CoA in mitochondria via the reductase-dependent pathway, enzyme is not involved in the isomerase-dependent pathway, overview
-
-
?
additional information
?
-