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1.3.1.15: dihydroorotate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (NADP+), go to the full flat file.

Reaction

(S)-dihydroorotate
+
NADP+
=
Orotate
+
NADPH
+
H+

Synonyms

reductase, orotate (reduced nicotinamide adenine dinucleotide phosphate), triphosphopyridine-linked dihydroorotic dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.15 dihydroorotate dehydrogenase (NADP+)

pH Range

pH Range on EC 1.3.1.15 - dihydroorotate dehydrogenase (NADP+)

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.7 - 8.8
-
at pH 6.7 and 8.8: about 25% of activity maximum