Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.3.1.15: dihydroorotate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (NADP+), go to the full flat file.

Reaction

(S)-dihydroorotate
+
NADP+
=
Orotate
+
NADPH
+
H+

Synonyms

reductase, orotate (reduced nicotinamide adenine dinucleotide phosphate), triphosphopyridine-linked dihydroorotic dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.15 dihydroorotate dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.3.1.15 - dihydroorotate dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5-fluoroorotate + NADPH
(S)-5-fluorodihydroorotate + NADP+
show the reaction diagram
-
enzyme exhibits very weak oxidase activity
-
?
orotate + NADPH
(S)-dihydroorotate + NADP+
show the reaction diagram