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1.20.1.1: phosphonate dehydrogenase

This is an abbreviated version!
For detailed information about phosphonate dehydrogenase, go to the full flat file.

Word Map on EC 1.20.1.1

Reaction

phosphonate
+
NAD+
+
H2O
=
phosphate
+
NADH
+
H+

Synonyms

NAD-dependent phosphite dehydrogenase, NAD:phosphite oxidoreductase, phosphite dehydrogenase, PTDH, PtxD

ECTree

     1 Oxidoreductases
         1.20 Acting on phosphorus or arsenic in donors
             1.20.1 With NAD+ or NADP+ as acceptor
                1.20.1.1 phosphonate dehydrogenase

Reference

Reference on EC 1.20.1.1 - phosphonate dehydrogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Costas, A.M.G.; White, A.K.; Metcalf, W.W.
Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88
J. Biol. Chem.
276
17429-17436
2001
Pseudomonas stutzeri (O69054)
Manually annotated by BRENDA team
Vrtis, J.M.; White, A.K.; Metcalf, W.W.; van der Donk, W.A.
Phosphite dehydrogenase: An unusual phosphoryl transfer reaction
J. Am. Chem. Soc.
123
2672-2673
2001
Pseudomonas stutzeri
Manually annotated by BRENDA team
Woodyer, R.; van der Donk, W.A.; Zhao, H.
Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design
Biochemistry
42
11604-11614
2003
Pseudomonas stutzeri
Manually annotated by BRENDA team
Woodyer, R.; Wheatley, J.L.; Relyea, H.A.; Rimkus, S.; van der Donk, W.A.
Site-directed mutagenesis of active site residues of phosphite dehydrogenase
Biochemistry
44
4765-4774
2005
Pseudomonas stutzeri, Pseudomonas stutzeri WM 88
Manually annotated by BRENDA team
Relyea, H.A.; Vrtis, J.M.; Woodyer, R.; Rimkus, S.A.; van der Donk, W.A.
Inhibition and pH dependence of phosphite dehydrogenase
Biochemistry
44
6640-6649
2005
Pseudomonas stutzeri
Manually annotated by BRENDA team
Relyea, H.A.; van der Donk, W.A.
Mechanism and applications of phosphite dehydrogenase
Bioorg. Chem.
33
171-189
2005
Alcaligenes faecalis, Pseudomonas stutzeri, Pseudomonas stutzeri WM88
Manually annotated by BRENDA team
Johannes, T.W.; Woodyer, R.D.; Zhao, H.
Directed evolution of a thermostable phosphite dehydrogenase for NAD(P)H regeneration
Appl. Environ. Microbiol.
71
5728-5734
2005
Pseudomonas stutzeri
Manually annotated by BRENDA team
Johannes, T.W.; Woodyer, R.D.; Zhao, H.
Efficient regeneration of NADPH using an engineered phosphite dehydrogenase
Biotechnol. Bioeng.
96
18-26
2007
Pseudomonas stutzeri
Manually annotated by BRENDA team
Woodyer, R.; van der Donk, W.A.; Zhao, H.
Optimizing a biocatalyst for improved NAD(P)H regeneration: directed evolution of phosphite dehydrogenase
Comb. Chem. High Throughput Screen.
9
237-245
2006
Pseudomonas stutzeri
Manually annotated by BRENDA team
Woodyer, R.; Zhao, H.; van der Donk, W.A.
Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration
FEBS J.
272
3816-3827
2005
Pseudomonas stutzeri
Manually annotated by BRENDA team
Fogle, E.J.; van der Donk, W.A.
Pre-steady-state studies of phosphite dehydrogenase demonstrate that hydride transfer is fully rate limiting
Biochemistry
46
13101-13108
2007
Pseudomonas stutzeri, Pseudomonas stutzeri WW88
Manually annotated by BRENDA team
McLachlan, M.J.; Johannes, T.W.; Zhao, H.
Further improvement of phosphite dehydrogenase thermostability by saturation mutagenesis
Biotechnol. Bioeng.
99
268-274
2008
Pseudomonas stutzeri (O69054)
Manually annotated by BRENDA team
Liu, D.F.; Ding, H.T.; Du, Y.Q.; Zhao, Y.H.; Jia, X.M.
Cloning, expression, and characterization of a wide-pH-range stable phosphite dehydrogenase from Pseudomonas sp. K in Escherichia coli
Appl. Biochem. Biotechnol.
166
1301-1313
2012
Pseudomonas sp. (F2YGD2), Pseudomonas sp., Pseudomonas sp. K (F2YGD2)
Manually annotated by BRENDA team
Hung, J.E.; Fogle, E.J.; Christman, H.D.; Johannes, T.W.; Zhao, H.; Metcalf, W.W.; van der Donk, W.A.
Investigation of the role of Arg301 identified in the X-ray structure of phosphite dehydrogenase
Biochemistry
51
4254-4262
2012
Cupriavidus metallidurans, Cupriavidus metallidurans CH34, Methylorubrum extorquens, Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1, Nostoc punctiforme, Pseudomonas stutzeri (O69054), Pseudomonas stutzeri
Manually annotated by BRENDA team
Zou, Y.; Zhang, H.; Brunzelle, J.S.; Johannes, T.W.; Woodyer, R.; Hung, J.E.; Nair, N.; van der Donk, W.A.; Zhao, H.; Nair, S.K.
Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration
Biochemistry
51
4263-4270
2012
Pseudomonas stutzeri (O69054)
Manually annotated by BRENDA team
Hirota, R.; Yamane, S.T.; Fujibuchi, T.; Motomura, K.; Ishida, T.; Ikeda, T.; Kuroda, A.
Isolation and characterization of a soluble and thermostable phosphite dehydrogenase from Ralstonia sp. strain 4506
J. Biosci. Bioeng.
113
445-450
2012
Pseudomonas stutzeri, Ralstonia sp. (G4XDR8), Ralstonia sp., Pseudomonas stutzeri WM88, Ralstonia sp. 4506 (G4XDR8)
Manually annotated by BRENDA team
Beyer, N.; Kulig, J.K.; Bartsch, A.; Hayes, M.A.; Janssen, D.B.; Fraaije, M.W.
P450BM3 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations
Appl. Microbiol. Biotechnol.
101
2319-2331
2017
Pseudomonas stutzeri, Pseudomonas stutzeri WM88
Manually annotated by BRENDA team
Ranaghan, K.; Hung, J.; Bartlett, G.; Mooibroek, T.; Harvey, J.; Woolfson, D.; Van Der Donk, W.; Mulholland, A.
A catalytic role for methionine revealed by a combination of computation and experiments on phosphite dehydrogenase
Chem. Sci.
5
2191-2199
2014
Pseudomonas stutzeri (O69054), Pseudomonas stutzeri WM88 (O69054)
-
Manually annotated by BRENDA team
Kanda, K.; Ishida, T.; Hirota, R.; Ono, S.; Motomura, K.; Ikeda, T.; Kitamura, K.; Kuroda, A.
Application of a phosphite dehydrogenase gene as a novel dominant selection marker for yeasts
J. Biotechnol.
182-183
68-73
2014
Ralstonia sp.
Manually annotated by BRENDA team
Hung, J.E.; Fogle, E.J.; Garg, N.; Chekan, J.R.; Nair, S.K.; van der Donk, W.A.
Chemical rescue and inhibition studies to determine the role of Arg301 in phosphite dehydrogenase
PLoS ONE
9
e87134
2014
Pseudomonas stutzeri (O69054), Pseudomonas stutzeri WM88 (O69054)
Manually annotated by BRENDA team