1.2.99.7: aldehyde dehydrogenase (FAD-independent)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (FAD-independent), go to the full flat file.

Reaction

Synonyms

aldehyde oxidase, aldehyde oxidoreductase, AOR, AORDd, BV-AIDH, DgAOR, MOP, MOP molybdenum-containing protein

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.99 With unknown physiological acceptors

                1.2.99.7 aldehyde dehydrogenase (FAD-independent)

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Results	in table
319	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
3	Cofactor
6	Crystallization (Commentary)
12	Inhibitors
8	kcat/KM [mM/s]
4	Ki Value [mM]
28	KM Value [mM]
27	Metals/Ions
7	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
22	Organism
1	Oxidation Stability
9	PDB ID
2	pH Optimum
12	Purification (Commentary)
1	Reaction
3	Reaction Type
21	Reference
3	Specific Activity [micromol/min/mg]
1	Storage Stability
65	Substrates and Products (Substrate)
6	Subunits
15	Synonyms
1	Systematic Name
1	Temperature Range [°C]
17	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.2.99.7 - aldehyde dehydrogenase (FAD-independent)

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2-phenylacetaldehyde

Megalodesulfovibrio gigas

Q46509

substrate inhibition at high concentrations

740765

3-phenylpropanal

Megalodesulfovibrio gigas

Q46509

substrate inhibition at high concentrations, suicide substrate

740765

arsenite

2 entries

benzaldehyde

Megalodesulfovibrio gigas

Q46509

substrate inhibition at high concentrations

740765

cinnamaldehyde

Megalodesulfovibrio gigas

Q46509

substrate inhibition at high concentrations

740765

cyanide

Megalodesulfovibrio gigas

Q46509

competitive reversible inhibitor, 30.9% inhibition at 50 mM

712240

ethylene glycol

Megalodesulfovibrio gigas

Q46509

mixed-type reversible inhibitor, 21.9% inhibition at 1 mM

712240

glycerol

Megalodesulfovibrio gigas

Q46509

competitive reversible inhibitor, 52% inhibition at 1 mM

712240

iodoacetate

Megalodesulfovibrio gigas

-

5 mM, complete inhibition

11936

KCN

Megalodesulfovibrio gigas

-

5 mM, 64% inhibition

11936

methanol

Megalodesulfovibrio gigas

-

1 M, 62% inhibition

11936

arsenite

Megalodesulfovibrio gigas

-

5 mM, complete inhibition

11936

arsenite

Megalodesulfovibrio gigas

Q46509

irreversible inhibitor, complete inhibition at 0.024 mM

712240