1.2.7.4: anaerobic carbon-monoxide dehydrogenase
This is an abbreviated version!
For detailed information about anaerobic carbon-monoxide dehydrogenase, go to the full flat file.
Word Map on EC 1.2.7.4
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1.2.7.4
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co2
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codhs
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nickel
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acetogenic
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thermoaceticum
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rubrum
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rhodospirillum
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methanosarcina
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carboxydothermus
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hydrogenoformans
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carboxidovorans
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c-clusters
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oligotropha
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wood-ljungdahl
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co-dependent
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methanogenesis
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carboxydotrophic
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co-oxidizing
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hydrogenases
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barkeri
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sulfate-reducing
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nickel-dependent
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acetobacterium
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nifes
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molybdenum-containing
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hydrogenogenic
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acetogenesis
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nickel-containing
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syngas
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methyl-coenzyme
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moorella
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square-planar
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homoacetogenic
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overpotential
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acetate-grown
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fe-containing
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electrocatalysts
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analysis
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hydrogenophaga
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methyltetrahydrofolate
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cubane-type
- 1.2.7.4
- co2
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codhs
- nickel
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acetogenic
- thermoaceticum
- rubrum
- rhodospirillum
- methanosarcina
- carboxydothermus
- hydrogenoformans
- carboxidovorans
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c-clusters
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oligotropha
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wood-ljungdahl
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co-dependent
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methanogenesis
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carboxydotrophic
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co-oxidizing
- hydrogenases
- barkeri
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sulfate-reducing
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nickel-dependent
- acetobacterium
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nifes
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molybdenum-containing
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hydrogenogenic
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acetogenesis
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nickel-containing
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syngas
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methyl-coenzyme
- moorella
-
square-planar
-
homoacetogenic
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overpotential
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acetate-grown
-
fe-containing
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electrocatalysts
- analysis
-
hydrogenophaga
- methyltetrahydrofolate
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cubane-type
Reaction
Synonyms
acetyl coenzyme A synthase/carbon monoxide dehydrogenase, acetyl-CoA synthase/carbon monoxide dehydrogenase, ACS/CODH, Carbon dioxide/carbon monoxide oxidoreductase, Carbon monoxide dehydrogenase, carbon monoxide dehydrogenase-corrinoid enzyme complex, carbon monoxide dehydrogenase/acetyl-CoA synthase, Carbon monoxide oxidoreductase, Cdh, CO dehydrogenase, CO dehydrogenase complex, CO dehydrogenase complex II, CO dehydrogenase II, CO dehydrogenase/acetyl-CoA synthase, Co-DG, CO-DH, CODH, CODH II, CODH-II, CODH/ACS, CODHACS, CODHase, CODHII, coos, Dehydrogenase, carbon monoxide, EC 1.2.99.2, monoxide dehydrogenase/acetyl-CoA synthase, Ni,Fe-CODH, Ni,Fe-dependent carbon monoxide dehydrogenase, Ni-CODH, Ni-containing carbon monoxide dehydrogenase, Ni-Fe carbon monoxide dehydrogenase II
ECTree
1.2.7.4 anaerobic carbon-monoxide dehydrogenaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 1.2.7.4 - anaerobic carbon-monoxide dehydrogenase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
CO + ferredoxin
?
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ferredoxin is the direct electron acceptor, the carbon-monoxide dehydrogenase complex reduces a ferredoxin which, together with membranes and associated hydrogenase, reconstitutes a CO-oxidizing:H2-evolving system
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?
CO + H2O + acceptor
CO2 + reduced acceptor + H+
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-
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?
CO + H2O + electron acceptor
CO2 + reduced electron acceptor
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a proton gradient across the cytoplasmic membrane is generated by channeling the electrons formed via cytochrome b561 into a CO-insensitive respiratory chain
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?
CO + H2O + oxidized cytochrome b
CO2 + reduced cytochrome b
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membrane-bound b-type, native electron carrier
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-
?
additional information
?
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-
Thermacetogenium phaeum operates the CO dehydrogenase/acetyl-CoA pathway reversibly both in acetate oxidation and in reductive acetogenesis by using the same biochemical apparatus
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-
?
CO + H2O + acceptor
CO2 + reduced acceptor
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-
-
?
CO + H2O + acceptor
CO2 + reduced acceptor
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-
-
?
CO + H2O + acceptor
CO2 + reduced acceptor
D5G1Y2; D5G1Y0; D5G1Y1
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-
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?
CO + H2O + electron acceptor
?
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the physiological role of the enzyme in acetyl-CoA synthesis is the reduction of CO2 to a bound CO, the physiological electron acceptor is not known and may be different in different organisms
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?
CO + H2O + electron acceptor
?
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key enzyme in C1-pathway of acetyl-CoA degradation
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-
?
CO + H2O + electron acceptor
?
Autotrophic methanogenic bacterium
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the enzyme is required for autotrophic CO2 fixation in methanogens, the enzyme is also involved in methanogenesis from acetate, not required for methanogenesis
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-
?
CO + H2O + electron acceptor
?
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the carbon monoxide dehydrogenase-corrinoid enzyme complex catalyzes the methylation of tetrahydrosarcinapterin in a reaction involving net cleavage of acetyl-CoA
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?
CO + H2O + electron acceptor
?
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enzyme may also be involved in the formation of acetyl-CoA from methanol in methanogens
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?
CO + H2O + electron acceptor
?
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extensive role of the enzyme in the acetyl-CoA pathway, it is proposed that the enzyme serves as the CO, CH3, SCoA acceptor and catalyzes the final steps of the synthesis of acetyl-CoA
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-
?
CO + H2O + electron acceptor
?
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the enzyme is involved in the Wood pathway of acetyl-CoA synthesis
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?
CO + H2O + electron acceptor
?
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delivery of a low-potential electron to the CO-bound NiFe complex is the physiological function of the CO oxidation reaction catalyzed by the enzyme
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?
CO + H2O + electron acceptor
?
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the formation of acetyl-CoA from methyltetrahydrofolate requires several enzymes, including CO dehydrogenase
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?
CO + H2O + electron acceptor
?
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ferredoxin and a membrane-bound b-type cytochrome are considered to be the native electron carriers
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?
CO + H2O + electron acceptor
?
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catalyzes the final step in the synthesis of acetyl-CoA
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?
CO + H2O + electron acceptor
?
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the physiological role of the enzyme in acetyl-CoA synthesis is the reduction of CO2 to a bound CO, the physiological electron acceptor is not known and may be different in different organisms
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-
?
CO + H2O + electron acceptor
?
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key role of the enzyme in the synthesis of acetyl-CoA
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?
CO + H2O + oxidized ferredoxin
CO2 + reduced ferredoxin
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may participate in methanogenesis by cleavage of acetate, reverse of the reaction in acetate biosynthesis
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?
CO + H2O + oxidized ferredoxin
CO2 + reduced ferredoxin
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acetate biosynthesis pathway, catalyzes an exchange reaction between CO and the carbonyl group of acetyl-CoA
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?
CO + H2O + oxidized ferredoxin
CO2 + reduced ferredoxin
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initial step of CO metabolism in acetogenic bacteria
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-
?
CO + H2O + oxidized ferredoxin
CO2 + reduced ferredoxin + H+
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-
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?
CO + H2O + oxidized ferredoxin
CO2 + reduced ferredoxin + H+
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-
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?
