1.2.7.12: formylmethanofuran dehydrogenase
This is an abbreviated version!
For detailed information about formylmethanofuran dehydrogenase, go to the full flat file.
Word Map on EC 1.2.7.12
-
1.2.7.12
-
methanogen
-
methanogenesis
-
methanobacterium
-
thermoautotrophicum
-
methanosarcina
-
molybdopterin
-
barkeri
-
heterodisulfide
-
formyltransferase
-
methanothermobacter
-
tungsten-containing
-
wolfei
-
molybdenum-containing
-
formylmethanofuran:tetrahydromethanopterin
-
molybdoenzyme
-
hydrogenotrophic
- 1.2.7.12
-
methanogen
-
methanogenesis
-
methanobacterium
- thermoautotrophicum
- methanosarcina
- molybdopterin
- barkeri
-
heterodisulfide
-
formyltransferase
- methanothermobacter
-
tungsten-containing
- wolfei
-
molybdenum-containing
-
formylmethanofuran:tetrahydromethanopterin
-
molybdoenzyme
-
hydrogenotrophic
Reaction
Synonyms
CHO-methanofuran dehydrogenase, CHO-MFR dehydrogenase, Dehydrogenase, formylmethanofuran, EC 1.2.99.5, Fmd, FmdE, formyl-methanofuran dehydrogenase, formyl-MFR dehydrogenase, Fwd, FWD1, FWD2, FwdA-DFGH/FwdAFmdBCE, molybdenum-type formylmethanofuran dehydrogenase, PF02663, tungsten-dependent formylmethanofuran dehydrogenase, tungsten-type formylmethanofuran dehydrogenase
ECTree
1.2.7.12 formylmethanofuran dehydrogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.2.7.12 - formylmethanofuran dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
CO2 + methanofuran + reduced acceptor
formylmethanofuran + H2O + acceptor
-
-
-
-
?
formylmethanofuran + H2O + ferredoxin
CO2 + methanofuran + reduced ferredoxin
-
-
-
-
?
formylmethanofuran + H2O + oxidized carbamoylviologen
CO2 + methanofuran + reduced carbamoylviologen
-
-
-
-
r
formylmethanofuran + H2O + oxidized ferredoxin
CO2 + methanofuran + reduced ferredoxin
-
-
-
-
r
formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster
CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
formylmethanofuran + H2O + oxidized methyl viologen
CO2 + methanofuran + reduced methyl viologen + H+
-
-
-
-
r
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
formylmethanofuran + oxidized acceptor
?
-
formation of formylmethanofuran, which is an intermediate in methanogenesis from CO2
-
-
?
formylmethanofuran + oxidized benzylviologen + H2O
methanofuran + reduced benzylviologen + CO2
formylmethanofuran + oxidized carbamoylmethylviologen + H2O
methanofuran + reduced carbamoylmethylviologen + CO2
-
-
-
?
formylmethanofuran + oxidized methylviologen + H2O
methanofuran + reduced methylviologen + CO2
CO2 + methanofuran + reduced ferredoxin
formylmethanofuran + H2O + oxidized ferredoxin
-
-
-
-
?
CO2 + methanofuran + reduced ferredoxin
formylmethanofuran + H2O + oxidized ferredoxin
-
-
-
-
?
Formamide + oxidized acceptor
?
-
molybdenum enzyme, 0.1% of the activity relative to formylmethanofuran
-
-
?
Formate + oxidized acceptor
?
-
molybdenum enzyme, 1% of the activity relative to formylmethanofuran
-
-
?
Formate + oxidized acceptor
?
-
molybdenum enzyme, 3% of the activity relative to formylmethanofuran
-
-
?
formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster
CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
-
-
-
-
?
formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster
CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
-
-
-
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
-
-
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
-
-
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
r
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
tungsten enzymes are specific for N-formylmethanofuran
-
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
molybdenum enzyme is specific for N-formylmethanofuran
-
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
-
-
-
?
formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen
CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen
-
tungsten enzymes are specific for N-formylmethanofuran
-
-
?
formylmethanofuran + oxidized benzylviologen + H2O
methanofuran + reduced benzylviologen + CO2
-
r
-
-
?
formylmethanofuran + oxidized benzylviologen + H2O
methanofuran + reduced benzylviologen + CO2
-
-
-
?
formylmethanofuran + oxidized benzylviologen + H2O
methanofuran + reduced benzylviologen + CO2
-
-
-
-
?
formylmethanofuran + oxidized methylviologen + H2O
methanofuran + reduced methylviologen + CO2
-
-
-
-
?
formylmethanofuran + oxidized methylviologen + H2O
methanofuran + reduced methylviologen + CO2
-
-
-
?
formylmethanofuran + oxidized methylviologen + H2O
methanofuran + reduced methylviologen + CO2
-
-
-
-
?
formylmethanofuran + oxidized methylviologen + H2O
methanofuran + reduced methylviologen + CO2
-
-
-
-
?
formylmethanofuran + oxidized methylviologen + H2O
methanofuran + reduced methylviologen + CO2
-
-
-
-
?
N-Furfurylformamide + oxidized acceptor
?
-
molybdenum enzyme, 11% of the activity relative to formylmethanofuran
-
-
?
N-Furfurylformamide + oxidized acceptor
?
-
-
-
-
?
N-Furfurylformamide + oxidized acceptor
?
-
molybdenum enzyme, 1% of the activity relative to formylmethanofuran
-
-
?
N-Methylformamide + oxidized acceptor
?
-
molybdenum enzyme, 0.2% of the activity relative to formylmethanofuran
-
-
?
additional information
?
-
-
during growth on medium supplemented with selenium only the isoenzyme with selenocysteine at the active site is transcribed. In selenium-deprived medium two tungsten-containing isoenzymes are transcribed
-
-
?
additional information
?
-
-
no activity with coenzyme F420 as electron acceptor
-
-
?
additional information
?
-
-
enzyme is involved in methanogenesis
-
-
?
additional information
?
-
-
no reduction of metronidazole, methylene blue, FAD or coenzyme F420 with formylmethanofuran
-
-
?
additional information
?
-
-
initial step of methanogenesis
-
-
?
additional information
?
-
-
the tungsten-containing isoenzyme is constitutively transcribed, the transcription of the molybdenum operon is induced by molybdate
-
-
?
