1.2.7.12: formylmethanofuran dehydrogenase

This is an abbreviated version!
For detailed information about formylmethanofuran dehydrogenase, go to the full flat file.

Word Map on EC 1.2.7.12

1.2.7.12

methanogen

methanogenesis

methanobacterium

thermoautotrophicum

methanosarcina

molybdopterin

barkeri

heterodisulfide

formyltransferase

methanothermobacter

tungsten-containing

wolfei

molybdenum-containing

formylmethanofuran:tetrahydromethanopterin

molybdoenzyme

hydrogenotrophic

Reaction

+ 2 oxidized ferredoxin [iron-sulfur] cluster =

+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+

Synonyms

CHO-methanofuran dehydrogenase, CHO-MFR dehydrogenase, Dehydrogenase, formylmethanofuran, EC 1.2.99.5, Fmd, FmdE, formyl-methanofuran dehydrogenase, formyl-MFR dehydrogenase, Fwd, FWD1, FWD2, FwdA-DFGH/FwdAFmdBCE, molybdenum-type formylmethanofuran dehydrogenase, PF02663, tungsten-dependent formylmethanofuran dehydrogenase, tungsten-type formylmethanofuran dehydrogenase

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.7 With an iron-sulfur protein as acceptor

1.2.7.12 formylmethanofuran dehydrogenase

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Results	in table
2393	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
4	Cofactor
3	Crystallization (Commentary)
1	Expression
8	General Information
1	General Stability
4	Inhibitors
40	KM Value [mM]
1	Localization
43	Metals/Ions
30	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
106	Organism
9	Pathway
2	PDB ID
10	pH Optimum
1	pH Range
3	pI Value
10	Purification (Commentary)
4	Reaction
2	Reaction Type
45	Reference
5	Source Tissue
9	Specific Activity [micromol/min/mg]
57	Substrates and Products (Substrate)
9	Subunits
29	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
1	Turnover Number [1/s]

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Natural Substrates Products on EC 1.2.7.12 - formylmethanofuran dehydrogenase

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CO2 + methanofuran + reduced acceptor

formylmethanofuran + H2O + acceptor

Methanosarcina acetivorans

739961

CO2 + methanofuran + reduced ferredoxin

formylmethanofuran + H2O + oxidized ferredoxin

2 entries

formylmethanofuran + H2O + ferredoxin

CO2 + methanofuran + reduced ferredoxin

Methanosarcina barkeri

741352

formylmethanofuran + H2O + oxidized ferredoxin

CO2 + methanofuran + reduced ferredoxin

Methanosarcina acetivorans

711603

formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster

CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster

2 entries

formylmethanofuran + oxidized acceptor

Methanosarcina barkeri

formation of formylmethanofuran, which is an intermediate in methanogenesis from CO2

11933

additional information

6 entries