1.2.7.12: formylmethanofuran dehydrogenase
This is an abbreviated version!
For detailed information about formylmethanofuran dehydrogenase, go to the full flat file.
Word Map on EC 1.2.7.12
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1.2.7.12
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methanogen
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methanogenesis
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methanobacterium
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thermoautotrophicum
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methanosarcina
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molybdopterin
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barkeri
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heterodisulfide
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formyltransferase
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methanothermobacter
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tungsten-containing
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wolfei
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molybdenum-containing
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formylmethanofuran:tetrahydromethanopterin
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molybdoenzyme
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hydrogenotrophic
- 1.2.7.12
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methanogen
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methanogenesis
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methanobacterium
- thermoautotrophicum
- methanosarcina
- molybdopterin
- barkeri
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heterodisulfide
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formyltransferase
- methanothermobacter
-
tungsten-containing
- wolfei
-
molybdenum-containing
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formylmethanofuran:tetrahydromethanopterin
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molybdoenzyme
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hydrogenotrophic
Reaction
+ + 2 oxidized ferredoxin [iron-sulfur] cluster = + + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
Synonyms
CHO-methanofuran dehydrogenase, CHO-MFR dehydrogenase, Dehydrogenase, formylmethanofuran, EC 1.2.99.5, Fmd, FmdE, formyl-methanofuran dehydrogenase, formyl-MFR dehydrogenase, Fwd, FWD1, FWD2, FwdA-DFGH/FwdAFmdBCE, molybdenum-type formylmethanofuran dehydrogenase, PF02663, tungsten-dependent formylmethanofuran dehydrogenase, tungsten-type formylmethanofuran dehydrogenase
ECTree
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Natural Substrates Products on EC 1.2.7.12 - formylmethanofuran dehydrogenase
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REACTION DIAGRAM
CO2 + methanofuran + reduced acceptor
formylmethanofuran + H2O + acceptor
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formylmethanofuran + H2O + ferredoxin
CO2 + methanofuran + reduced ferredoxin
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formylmethanofuran + H2O + oxidized ferredoxin
CO2 + methanofuran + reduced ferredoxin
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r
formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster
CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
formylmethanofuran + oxidized acceptor
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formation of formylmethanofuran, which is an intermediate in methanogenesis from CO2
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formylmethanofuran + H2O + oxidized ferredoxin
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CO2 + methanofuran + reduced ferredoxin
formylmethanofuran + H2O + oxidized ferredoxin
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CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
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formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster
CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
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during growth on medium supplemented with selenium only the isoenzyme with selenocysteine at the active site is transcribed. In selenium-deprived medium two tungsten-containing isoenzymes are transcribed
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additional information
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enzyme is involved in methanogenesis
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additional information
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initial step of methanogenesis
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additional information
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the tungsten-containing isoenzyme is constitutively transcribed, the transcription of the molybdenum operon is induced by molybdate
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