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1.2.7.12: formylmethanofuran dehydrogenase

This is an abbreviated version!
For detailed information about formylmethanofuran dehydrogenase, go to the full flat file.

Word Map on EC 1.2.7.12

Reaction

a formylmethanofuran
+
H2O
 + 2 oxidized ferredoxin [iron-sulfur] cluster =
CO2
 +
a methanofuran
 + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+

Synonyms

CHO-methanofuran dehydrogenase, CHO-MFR dehydrogenase, Dehydrogenase, formylmethanofuran, EC 1.2.99.5, Fmd, FmdE, formyl-methanofuran dehydrogenase, formyl-MFR dehydrogenase, Fwd, FWD1, FWD2, FwdA-DFGH/FwdAFmdBCE, molybdenum-type formylmethanofuran dehydrogenase, PF02663, tungsten-dependent formylmethanofuran dehydrogenase, tungsten-type formylmethanofuran dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.7 With an iron-sulfur protein as acceptor
                1.2.7.12 formylmethanofuran dehydrogenase

Expression

Expression on EC 1.2.7.12 - formylmethanofuran dehydrogenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
the molybdenum-type formylmethanofuran dehydrogenase operon reporter genes fmdE1 and fmdA1 are expressed at 14fold higher levels during methanol growth conditions relative to acetate growth. Genes fmdF2, fmdA2, and fmdB2 are expressed about 2fold higher during these conditions, but the maximal level of expression is less than 5% of that seen for the fmdE1 and fmdA1 genes. The tungsten-type formylmethanofuran dehydrogenase genes fwdB1 and fwdA1 are also expressed 15fold higher levels during methanol growth relative to acetate
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