1.2.1.95: L-2-aminoadipate reductase

This is an abbreviated version!
For detailed information about L-2-aminoadipate reductase, go to the full flat file.

Reaction

Synonyms

AAR, AarA, AasS, alpha-AAR, alpha-aminoadipate delta-semialdehyde synthase, alpha-aminoadipate reductase, L-alpha-aminoadipic acid reductase, Lys1+, LYS2, Nps3

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.95 L-2-aminoadipate reductase

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1	Activating Compound
1274	AA Sequence
2	Application
7	Cloned(Commentary)
5	Cofactor
3	Expression
5	General Information
5	Inhibitors
4	kcat/KM [mM/s]
1	Ki Value [mM]
11	KM Value [mM]
4	Metals/Ions
6	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
17	Organism
3	Pathway
1	pH Optimum
1	pH Range
3	Posttranslational Modification
73	Protein Variants
2	Purification (Commentary)
3	Reaction
17	Reference
1	Source Tissue
2	Storage Stability
13	Substrates and Products (Substrate)
4	Subunits
25	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
5	Turnover Number [1/s]

Reaction

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Reaction on EC 1.2.1.95 - L-2-aminoadipate reductase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

(S)-2-amino-6-oxohexanoate + holo-[LYS2 peptidyl-carrier-protein] + NADP+ = L-2-aminoadipyl-[LYS2 peptidyl-carrier-protein] + NADPH + H+

(1b)

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(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate = L-2-aminoadipate + NADPH + H+ + ATP

overall reaction

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L-2-aminoadipyl-[LYS2 peptidyl-carrier-protein] + AMP + diphosphate = L-2-aminoadipate + holo-[LYS2 peptidyl-carrier-protein] + ATP

(1a)

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