1.2.1.91: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
This is an abbreviated version!
For detailed information about 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase, go to the full flat file.
Reaction
Synonyms
EC 1.17.1.7, oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase (NADP+), paaZ, PaaZ-ALDH, PacL
ECTree
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Systematic Name
Systematic Name on EC 1.2.1.91 - 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
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3-oxo-5,6-dehydrosuberyl-CoA semialdehyde:NADP+ oxidoreductase
The enzyme from Escherichia coli is a bifunctional fusion protein that also catalyses EC 3.3.2.12, oxepin-CoA hydrolase. Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway.