1.2.1.39: phenylacetaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about phenylacetaldehyde dehydrogenase, go to the full flat file.

Reaction

Synonyms

dehydrogenase, phenylacetaldehyde, ebA4954, feaB, NAD(P)+-dependent phenylacetaldehyde dehydrogenase, NPADH, PAAL dehydrogenase, PAD, PadA, PADH, PDH, PeaE, PeaE protein, phenylacetaldehyde dehydrogenase, styD

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.39 phenylacetaldehyde dehydrogenase

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Results	in table
1086	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
31	Cofactor
1	Crystallization (Commentary)
11	General Information
1	General Stability
30	Inhibitors
2	kcat/KM [mM/s]
2	Ki Value [mM]
27	KM Value [mM]
2	Localization
13	Metals/Ions
10	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
49	Organism
13	Pathway
4	PDB ID
5	pH Optimum
1	pH Range
2	pH Stability
9	Purification (Commentary)
3	Reaction
4	Reaction Type
32	Reference
1	Source Tissue
7	Specific Activity [micromol/min/mg]
5	Storage Stability
114	Substrates and Products (Substrate)
12	Subunits
43	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.2.1.39 - phenylacetaldehyde dehydrogenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

4-hydroxyphenylacetaldehyde + NAD+ + H2O

4-hydroxyphenylacetate + NADH + H+

2 entries

phenylacetaldehyde + NAD+ + H2O

?

14 entries

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

11 entries

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + H+

5 entries

phenylacetaldehyde + NAD+ + H2O

phenylacetic acid + NADH + H+

Pseudomonas putida

B1N7H3

-

686425

-

-

?

4-hydroxyphenylacetaldehyde + NAD+ + H2O

4-hydroxyphenylacetate + NADH + H+

Escherichia coli

-

-

725180

-

-

?

4-hydroxyphenylacetaldehyde + NAD+ + H2O

4-hydroxyphenylacetate + NADH + H+

Escherichia coli

P80668

-

724020

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Achromobacter eurydice

-

inducible enzyme appears when cells are grown on L-phenylalanine or on L-tryptophan as sole source of carbon

390292

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Bacteria

-

involved in degradation of styrene

390293

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Bacteria S5

-

involved in degradation of styrene

390293

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Escherichia coli

-

inducible enzyme of 2-phenylethylamine catabolism

390296

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Escherichia coli

-

a positive regulatory protein required for expression of phenylacetaldehyde dehydrogenase is located next to the PAD gene

390300

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Escherichia coli

-

enzyme is involved in the catabolism of 2-phenylethylamine

390299, 390300

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Flavobacterium sp.

-

involved in DL-phenylacrylic acid and phenylacetic acid catabolism

7426

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Pseudomonas putida

-

enzyme is involved in degradation of styrene. Low constitutive levels of NAD+-dependent phenylacetaldehyde dehydrogenase

390301

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Pseudomonas putida CA-3

-

enzyme is involved in degradation of styrene. Low constitutive levels of NAD+-dependent phenylacetaldehyde dehydrogenase

390301

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Pseudomonas sp.

-

enzyme is involved in metabolism of atropine

390298

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Pseudomonas sp. AT3

-

enzyme is involved in metabolism of atropine

390298

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Thauera aromatica

-

enzyme is involved in the anaerobic metabolism of L-phenylalanine

718

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Xanthobacter sp.

-

inolved in degradation of styrene oxide and 2-phenylethanol

390294

-

-

?

phenylacetaldehyde + NAD+ + H2O

?

Xanthobacter sp. 124X

-

inolved in degradation of styrene oxide and 2-phenylethanol

390294

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Aromatoleum aromaticum

Q5P171

-

742786

-

-

r

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Aromatoleum aromaticum EbN1

Q5P171

-

742786

-

-

r

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Escherichia coli

P80668

-

762619, 762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Gordonia rubripertincta

-

-

762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Gordonia rubripertincta CWB2

-

-

762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Pseudomonas putida

V4GH04

-

741787

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Pseudomonas putida S12

V4GH04

-

741787

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Rhodococcus opacus

-

-

762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Rhodococcus opacus 1CP

-

-

762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Sphingopyxis fribergensis

A0A0A7PB40

-

762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + 2 H+

Sphingopyxis fribergensis Kp5.2

A0A0A7PB40

-

762624

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + H+

Brevibacterium sp.

-

-

690567

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + H+

Brevibacterium sp. KU1309

-

-

690567

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + H+

Escherichia coli

P80668

-

724020

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + H+

Escherichia coli

-

the enzyme participates in metabolism of phenylalanine

670833

-

-

?

phenylacetaldehyde + NAD+ + H2O

phenylacetate + NADH + H+

Pseudomonas putida

B1N7H3

-

686425

-

-

?