1.2.1.3: aldehyde dehydrogenase (NAD+)

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For detailed information about aldehyde dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.2.1.3

1.2.1.3

aldhs

retinoic

metastasis

self-renewal

isozymes

stem-like

smoke

esophageal

drinker

nanog

flush

myocardial

east

retinaldehyde

tumorigenic

clinicopathological

case-control

smoking

colorectal

epithelial-mesenchymal

cyp2e1

chemoresistance

spheroid

alcohol-induced

disulfiram

mesenchymal

alcohol-related

sphere

detoxify

habit

nitroglycerin

cell-like

4-hydroxy-2-nonenal

tumor-initiating

trinitrate

mammosphere

keratocytes

csc-like

sphere-forming

cyanamide

aerodigestive

non-drinkers

epcam

glyceryl

alcohol-dependent

tumorsphere

chloral

analysis

dehydrogenase-1

synthesis

low-km

medicine

ichthyosis

Reaction

Synonyms

ADH, AdhE, AHD-M1, ALD1A1, ALD4, ALD6, ALDDH, aldehyde dehydrogenase, aldehyde dehydrogenase (NAD), aldehyde dehydrogenase 1, aldehyde dehydrogenase 16, aldehyde dehydrogenase 1A1, aldehyde dehydrogenase 1A3, aldehyde dehydrogenase 1B1, aldehyde dehydrogenase 2, aldehyde dehydrogenase 3A1, aldehyde dehydrogenase 6, aldehyde dehydrogenase 7A1, aldehyde dehydrogenase class 1, aldehyde dehydrogenase type 2, Aldehyde dehydrogenase [NAD+], Aldehyde dehydrogenase, cytosolic, Aldehyde dehydrogenase, microsomal, aldehyde dehydrogenase-2, aldehyde dehydrogenase7, aldehyde:NAD+ oxidoreductase, ALDH, ALDH 2, ALDH I, ALDH II, ALDH-2, ALDH-E1, ALDH-E2, ALDH1, ALDH1-NL, ALDH16, ALDH1A1, Aldh1a2, Aldh1a3, Aldh1a7, Aldh1b1, ALDH2, ALDH2(1), ALDH2(2), ALDH2(3), ALDH22A1, ALDH2B8, ALDH2C4, ALDH3A1, ALDH3A2, Aldh3b1, ALDH3H1, ALDH3I1, ALDH5A, ALDH7, Aldh7a1, ALDH7B4, Aldh8a1, ALDHI, ALDHTt, ALDHX, ALHDII, Allergen Alt a 10, aryl-aldehyde dehydrogenases, BADH, benzaldehyde dehydrogenase, Brassica turgor-responsive/drought-induced gene 26 protein, Bt-Aldh, Btg-26, class 1 aldehyde dehydrogenase, class 2 aldehyde dehydrogenase, class I ALDH, CoA-independent aldehyde dehydrogenase, coniferyl-aldehyde dehydrogenase, Cphy_1178, EC 1.1.1.70, ETA-crystallin, FeaB-K-12, gamma-aminobutyraldehyde dehydrogenase, hALDH2, HsALDH16A1, irreversible NAD+-dependent aldehyde dehydrogenase, K(+)-ACDH, K(+)-activated acetaldehyde dehydrogenase, KGSADH, LsALDH16, m-methylbenzaldehyde dehydrogenase, Matured fruit 60 kDa protein, MF-60, Mg(2+)-ACDH, Mg(2+)-activated acetaldehyde dehydrogenase, mitochondrial aldehyde dehydrogenase, More, NAD+-dependent aldehyde dehydrogenase, NAD+-dependent ALDH, NAD+-linked aldehyde dehydrogenase, NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase, NAD+-specific ALDH, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, Non-lens ALDH1, p-ALDH2, P51, phenylacetaldehyde dehydrogenase, PhnN, phnY, phosphonoacetaldehyde dehydrogenase, phosphonoacetaldehyde oxidase, PM-ALDH9, PnAA dehydrogenase, propionaldehyde dehydrogenase, PuuC, R-aminobutyraldehyde dehydrogenase, RALDH, RALDH(II), RalDH1, Retinal dehydrogenase, retinal dehydrogenase type I, sALDH, salvery aldehyde dehydrogenase, ThnG, TTC0513, Turgor-responsive protein 26G, yALDH, YneI

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.3 aldehyde dehydrogenase (NAD+)

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Results	in table
40	Activating Compound
20819	AA Sequence
16	Application
1	CAS Registry Number
70	Cloned(Commentary)
187	Cofactor
13	Crystallization (Commentary)
10146	Disease/ Diagnostics
16	Expression
43	General Information
6	General Stability
32	IC50 Value
286	Inhibitors
58	kcat/KM [mM/s]
29	Ki Value [mM]
553	KM Value [mM]
106	Localization
36	Metals/Ions
118	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
11	Organic Solvent Stability
261	Organism
1	Oxidation Stability
53	Pathway
513	PDB ID
49	pH Optimum
12	pH Range
13	pH Stability
8	pI Value
2	Posttranslational Modification
92	Protein Variants
86	Purification (Commentary)
7	Reaction
26	Reaction Type
213	Reference
235	Source Tissue
112	Specific Activity [micromol/min/mg]
12	Storage Stability
674	Substrates and Products (Substrate)
80	Subunits
331	Synonyms
1	Systematic Name
19	Temperature Optimum [°C]
3	Temperature Range [°C]
26	Temperature Stability [°C]
174	Turnover Number [1/s]

Purification

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Purification on EC 1.2.1.3 - aldehyde dehydrogenase (NAD+)

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11 entries

5'-AMP-Sepharose 4B affinity column chromatography, gel filtration