1.17.1.4: xanthine dehydrogenase

This is an abbreviated version!
For detailed information about xanthine dehydrogenase, go to the full flat file.

Reaction

Synonyms

AtXDH1, EC 1.1.1.204, EC 1.2.1.37, IAO1, More, NAD-xanthine dehydrogenase, PaoABC, Retinol dehydrogenase, Rosy locus protein, VvXDH, xanthine dehydrogenase, xanthine dehydrogenase-1, xanthine dehydrogenase-2, xanthine dehydrogenase/oxidase, xanthine oxidoreductase, xanthine-NAD oxidoreductase, xanthine/NAD+ oxidoreductase, xanthine:NAD+ oxidoreductase, XDH, XDH/XO, XDH1, XDH2, XdhC, XOR, YagR, YagS, YagT

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.1 With NAD⁺ or NADP⁺ as acceptor

                1.17.1.4 xanthine dehydrogenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
22	Activating Compound
13818	AA Sequence
34	Application
1	CAS Registry Number
36	Cloned(Commentary)
299	Cofactor
22	Crystallization (Commentary)
40	Disease/ Diagnostics
3	Expression
84	General Information
9	General Stability
175	Inhibitors
19	kcat/KM [mM/s]
3	Ki Value [mM]
170	KM Value [mM]
22	Localization
133	Metals/Ions
86	Molecular Weight [Da]
237	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
225	Organism
1	Oxidation Stability
14	Pathway
110	PDB ID
45	pH Optimum
8	pH Range
8	pH Stability
1	pI Value
4	Posttranslational Modification
79	Protein Variants
71	Purification (Commentary)
9	Reaction
3	Reaction Type
205	Reference
2	Renatured (Commentary)
217	Source Tissue
65	Specific Activity [micromol/min/mg]
8	Storage Stability
572	Substrates and Products (Substrate)
66	Subunits
107	Synonyms
1	Systematic Name
32	Temperature Optimum [°C]
1	Temperature Range [°C]
22	Temperature Stability [°C]
55	Turnover Number [1/s]

General Stability

print visible entries

print all entries

General Stability on EC 1.17.1.4 - xanthine dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to General Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

complete loss of activity when stored below 0°C

Gottschalkia acidurici

-

644592

conversion of xanthine oxidoreductase from dehydrogenase to oxidase form occurs in the presence of guanidine-HCl or urea. Both forms are in a thermodynamic equilibrium that can be shifted by disruption of the stabilizing amino acid cluster with a denaturant

2 entries

crude and purified enzyme preparations form readily insoluble inactive aggregates, not stable to freezing and thawing

Delftia acidovorans

-

644581

enzyme from crude extract can be stabilized by addition of nicotinamide, cysteine and EDTA, purified enzyme more stable

Streptomyces cyanogenus

-

644616

extremely labile

Drosophila melanogaster

-

644605

oxygen-linked activity rather unstable during storage at 4°C, ferricyanide-linked activity stable to freezing and thawing

Pseudomonas putida

-

644593

subunit alpha more sensitive to SDS-heat treatment

Gallus gallus

-

644572

treatment accelerating conversion of dehydrogenase type D to oxidase type O is lyophilization, storage at -20°C, exposure to 20% ammonium sulfate, 0.5 mM NAD+ or 0.01 mM xanthine

Rattus sp.

-

644580

conversion of xanthine oxidoreductase from dehydrogenase to oxidase form occurs in the presence of guanidine-HCl or urea. Both forms are in a thermodynamic equilibrium that can be shifted by disruption of the stabilizing amino acid cluster with a denaturant

Rattus norvegicus

-

689276

conversion of xanthine oxidoreductase from dehydrogenase to oxidase form occurs in the presence of guanidine-HCl or urea. Both forms are in a thermodynamic equilibrium that can be shifted by disruption of the stabilizing amino acid cluster with a denaturant

Bos taurus

-

689276