1.14.99.12: androst-4-ene-3,17-dione monooxygenase
This is an abbreviated version!
For detailed information about androst-4-ene-3,17-dione monooxygenase, go to the full flat file.
Word Map on EC 1.14.99.12
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1.14.99.12
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putida
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hydroxylases
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toluene
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catechol
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alpha-hydroxylase
- 1.14.99.12
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putida
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hydroxylases
- toluene
- catechol
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alpha-hydroxylase
Reaction
Synonyms
4-androstene-3,17-dione monooxygenase, androst-4-ene-3,17-dione 17-oxidoreductase, androst-4-ene-3,17-dione hydroxylase, androstene-3,17-dione hydroxylase, androstenedione monooxygenase, oxygenase, androstenedione mono-
ECTree
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Substrates Products
Substrates Products on EC 1.14.99.12 - androst-4-ene-3,17-dione monooxygenase
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REACTION DIAGRAM
androst-4-ene-3,17-dione + AH2 + O2
14alpha-hydroxyandrost-4-ene-3,17-dione + 14alpha,17beta-dihydroxyandrost-4-en-3-one + 7alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
androst-4-ene-3,17-dione + AH2 + O2
14alpha-hydroxyandrost-4-ene-3,17-dione + 6beta-hydroxyandrost-4-ene-3,17-dione + A + H2O
androst-4-ene-3,17-dione + AH2 + O2
17beta-hydroxyandrost-4-en-3-one + 11beta-hydroxyandrost-4-ene-3,17-dione + 17alpha-oxa-D-homo-androst-4-ene-3,17-dione + A + H2O
androst-4-ene-3,17-dione + AH2 + O2
17beta-hydroxyandrost-4-en-3-one + 14alpha-hydroxyandrost-4-ene-3,17-dione + 11alpha-hydroxyandrost-4-ene-3,17-dione + 15beta,17beta-dihydroxyandrost-4-en-3-one + 11alpha,17beta-dihydroxyandrost-4-en-3-one + 15alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
androst-4-ene-3,17-dione + AH2 + O2
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
androst-4-ene-3,17-dione + NADPH + O2
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + NADP+ + H2O
14alpha-hydroxyandrost-4-ene-3,17-dione + 14alpha,17beta-dihydroxyandrost-4-en-3-one + 7alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
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androst-4-ene-3,17-dione + AH2 + O2
14alpha-hydroxyandrost-4-ene-3,17-dione + 14alpha,17beta-dihydroxyandrost-4-en-3-one + 7alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
Mucor hiemalis MRC 70325
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?
14alpha-hydroxyandrost-4-ene-3,17-dione + 6beta-hydroxyandrost-4-ene-3,17-dione + A + H2O
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?
androst-4-ene-3,17-dione + AH2 + O2
14alpha-hydroxyandrost-4-ene-3,17-dione + 6beta-hydroxyandrost-4-ene-3,17-dione + A + H2O
Aspergillus wentii MRC 200316
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?
17beta-hydroxyandrost-4-en-3-one + 11beta-hydroxyandrost-4-ene-3,17-dione + 17alpha-oxa-D-homo-androst-4-ene-3,17-dione + A + H2O
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?
androst-4-ene-3,17-dione + AH2 + O2
17beta-hydroxyandrost-4-en-3-one + 11beta-hydroxyandrost-4-ene-3,17-dione + 17alpha-oxa-D-homo-androst-4-ene-3,17-dione + A + H2O
Aspergillus tamarii MRC 72400
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?
17beta-hydroxyandrost-4-en-3-one + 14alpha-hydroxyandrost-4-ene-3,17-dione + 11alpha-hydroxyandrost-4-ene-3,17-dione + 15beta,17beta-dihydroxyandrost-4-en-3-one + 11alpha,17beta-dihydroxyandrost-4-en-3-one + 15alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
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?
androst-4-ene-3,17-dione + AH2 + O2
17beta-hydroxyandrost-4-en-3-one + 14alpha-hydroxyandrost-4-ene-3,17-dione + 11alpha-hydroxyandrost-4-ene-3,17-dione + 15beta,17beta-dihydroxyandrost-4-en-3-one + 11alpha,17beta-dihydroxyandrost-4-en-3-one + 15alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
Aspergillus candidus MRC 200634
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?
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
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?
androst-4-ene-3,17-dione + AH2 + O2
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
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enzyme levels increase after exposure of rats to di-n-butyl phthalate
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3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + NADP+ + H2O
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testololactone
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androst-4-ene-3,17-dione + NADPH + O2
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + NADP+ + H2O
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testololactone
?