1.14.19.50: noroxomaritidine synthase
This is an abbreviated version!
For detailed information about noroxomaritidine synthase, go to the full flat file.
Reaction
Synonyms
CYP96T1
ECTree
1.14.19.50 noroxomaritidine synthaseAdvanced search results
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Substrates Products on EC 1.14.19.50 - noroxomaritidine synthase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(R)-coclaurine + [reduced NADPH-hemoprotein reductase] + O2
? + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
-
-
?
(S)-coclaurine + [reduced NADPH-hemoprotein reductase] + O2
? + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
-
-
?
4'-O-methyl-N-methylnorbelladine + [reduced NADPH-hemoprotein reductase] + O2
? + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
-
-
?
4'-O-methylnorbelladine + [reduced NADPH-hemoprotein reductase] + O2
(4aR,10bS)-noroxomaritidine + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
formation of the para-ortho' phenol coupled product, N-demethylnarwedine, at less than 1% of the total product
-
?
4'-O-methylnorbelladine + [reduced NADPH-hemoprotein reductase] + O2
(4aS,10bR)-noroxomaritidine + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
formation of the para-ortho' phenol coupled product, N-demethylnarwedine, at less than 1% of the total product
-
?
additional information
?
-
the enzyme catalyzes a C-C phenol-coupling reaction with para-paraΒ regiospecificity. No substrates: norbelladine, N-methylnorbelladine, 3'-O-methylnorbelladine, 3',4'-O-dimethylnorbelladine
-
-
?
