1.14.19.49: tetracycline 7-halogenase
This is an abbreviated version!
For detailed information about tetracycline 7-halogenase, go to the full flat file.
Reaction
Synonyms
ctcP, Cts4
ECTree
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General Information
General Information on EC 1.14.19.49 - tetracycline 7-halogenase
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physiological function
S4S3E1
chlorination by FADH2-dependent halogenase CtcP is the last inefficient step during chlortetracycline biosynthesis. A strain lacking CtcP activity accumulates tetracycline and is deficient in production of chlortetracycline
physiological function
expression of Cts4 complements a Streptomyces aureofaciens mutant deficient for chlorination of tetracycline
physiological function
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expression of Cts4 complements a Streptomyces aureofaciens mutant deficient for chlorination of tetracycline
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physiological function
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chlorination by FADH2-dependent halogenase CtcP is the last inefficient step during chlortetracycline biosynthesis. A strain lacking CtcP activity accumulates tetracycline and is deficient in production of chlortetracycline
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