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9.94
2-Methylresorcinol
-
pH 7.0, 25°C
554 - 632
3,4-dihydroxyphenyl propionic acid
5.9 - 433.1
3,4-dihydroxyphenylacetic acid
607.2
3,4-Dihydroxyphenylpropionic acid
-
-
544
3-(3,4-dihydroxyphenyl) propionic acid
-
3
3-(3,5-dihydroxyphenyl)-1-propanoic acid
recombinant enzyme, pH 7.2, 37°C
0.9
3-chlorophenol
-
in 100 mM phosphate buffer, pH 6.8, at 25°C
12.1
3-Hydroxybenzyl alcohol
-
-
6
3-[2-(3,4-dihydroxyphenyl)ethylaminocarbonyl]-3-methyl-1-(4-ethoxycarbonylphenyl)triazene
-
in phosphate buffer (pH 7.4), at 37°C
0.6
3-[2-(4-hydroxyphenyl)ethylaminocarbonyl]-3-methyl-1-(4-cyanophenyl)triazene
-
in phosphate buffer (pH 7.4), at 37°C
6.9
4-Bromophenol
-
pH and temperature not specified in the publication
859.2
4-Chlorocatechol
-
-
132 - 202.2
4-ethoxyphenol
802.3
4-Ethylcatechol
-
-
6
4-ethylresorcinol
-
pH 7.0, 25°C
10.5 - 10.54
4-Fluorophenol
184 - 274.9
4-hydroxyanisole
0.19
4-hydroxybenzaldehyde
-
pH and temperature not specified in the publication
20 - 88.2
4-Hydroxybenzyl alcohol
66.7 - 134
4-hydroxyphenyl propionic acid
44.3 - 250
4-hydroxyphenyl acetic acid
66.7
4-hydroxyphenyl propionic acid
-
-
43 - 66.7
4-hydroxyphenylpropionic acid
2.73
4-iodophenol
-
pH and temperature not specified in the publication
184 - 184.2
4-methoxyphenol
12 - 7220
4-methylcatechol
14.76
4-Methylphenol
-
pH and temperature not specified in the publication
7.73
4-methylresorcinol
-
pH 7.0, 25°C
20.5 - 1650
4-tert-butylcatechol
5.61
4-tert-butylphenol
-
pH and temperature not specified in the publication
4.43
alpha-arbutin
-
pH 7.0, 25°C
1650
chlorogenic acid
-
-
1.95
deoxyarbutin
pH and temperature not specified in the publication
4.48
diphenol
Helix vulgaris
-
-
0.6
DL-2-methyltyrosine
-
-
35.5
dopa methyl ester
-
-
1.5
H2O2
-
at pH 8.0 and 37°C
4630
Hydrocaffeic acid
-
-
101.5
hydroquinone
-
pH 7.0, 25°C
229
Hydroxyhydroquinone
-
pH and temperature not specified in the publication
0.6
L-alpha-methyl tyrosine
-
-
44.3
L-alpha-methyldopa
-
-
57 - 187
L-dopa methyl ester
2.28 - 29.4
L-isoproterenol
2.5 - 19.5
L-tyrosinase
-
3.4 - 235
L-tyrosine methyl ester
2.24 - 8.9
methyl 3-hydroxy-L-tyrosinate
5.39
oxyresveratrol
-
pH 7.0, 25°C
8.1 - 860
protocatechuic acid
1.5 - 336
Protocatechuic aldehyde
18.34
resorcinol
-
pH 7.0, 25°C
554
3,4-dihydroxyphenyl propionic acid
-
-
632
3,4-dihydroxyphenyl propionic acid
-
-
5.9
3,4-dihydroxyphenylacetic acid
recombinant enzyme, pH 7.2, 37°C
113
3,4-dihydroxyphenylacetic acid
recombinant enzyme, pH 7.2, 37°C
433.1
3,4-dihydroxyphenylacetic acid
-
-
4.6
4-Chlorophenol
-
pH and temperature not specified in the publication
5.6
4-Chlorophenol
-
in 100 mM phosphate buffer, pH 6.8, at 25°C
132
4-ethoxyphenol
-
-
132
4-ethoxyphenol
-
pH 7.0, 25°C
202.2
4-ethoxyphenol
-
pH and temperature not specified in the publication
10.5
4-Fluorophenol
-
-
10.54
4-Fluorophenol
-
pH and temperature not specified in the publication
184
4-hydroxyanisole
-
-
184.2
4-hydroxyanisole
-
pH 7.0, 25°C
274.9
4-hydroxyanisole
-
pH and temperature not specified in the publication
20 - 50
4-Hydroxybenzyl alcohol
-
-
88.2
4-Hydroxybenzyl alcohol
-
-
66.7
4-hydroxyphenyl propionic acid
-
-
134
4-hydroxyphenyl propionic acid
-
-
44.3
4-hydroxyphenyl acetic acid
-
-
48.8
4-hydroxyphenyl acetic acid
-
-
250
4-hydroxyphenyl acetic acid
-
-
43
4-hydroxyphenylpropionic acid
-
pH 6.8, 25°C, in methanol-glycerol cryosolvent
66.7
4-hydroxyphenylpropionic acid
-
pH 6.8, 25°C, in aqueous buffer
184
4-methoxyphenol
-
-
184.2
4-methoxyphenol
-
pH 7.0, 25°C
12
4-methylcatechol
recombinant enzyme, pH 7.2, 37°C
842.1
4-methylcatechol
-
-
7220
4-methylcatechol
-
-
20.5
4-tert-butylcatechol
recombinant enzyme, pH 7.2, 37°C
640.1
4-tert-butylcatechol
-
-
642
4-tert-butylcatechol
-
-
1650
4-tert-butylcatechol
recombinant enzyme, pH 7.2, 37°C
3.7
beta-arbutin
-
pH 7.0, 25°C
3.77
beta-arbutin
pH and temperature not specified in the publication
44
catechol
recombinant enzyme, pH 7.2, 37°C
80
catechol
recombinant enzyme, pH 7.2, 37°C
1080
catechol
pH 6.8, 25°C, recombinant enzyme
6
D-Dopa
-
in 50 mM potassium phosphate buffer (pH 7.0)
6.35
D-Dopa
-
wild type enzyme, in 50 mM Tris-HCl buffer pH 7.0, 0.01 mM CuSO4, 28°C
6.88
D-Dopa
-
mutant enzyme R209H, in 50 mM Tris-HCl buffer pH 7.0, 0.01 mM CuSO4, 28°C
12.12
D-Dopa
-
in 50 mM potassium phosphate buffer (pH 7.0), with 30% (v/v) DMSO
8
D-Tyr
-
-
0.3
D-tyrosine
wild type enzyme, at pH 7.0 and 30°C
0.63
D-tyrosine
random mutant enzyme RVC10, at pH 7.0 and 30°C
0.97
D-tyrosine
random mutant enzyme RV145, at pH 7.0 and 30°C
1.22
D-tyrosine
random mutant enzyme C10-N322S, at pH 7.0 and 30°C
1.27
D-tyrosine
random mutant enzyme 145-Y119F, at pH 7.0 and 30°C
1.35
D-tyrosine
random mutant enzyme 145-D317Y, at pH 7.0 and 30°C
1.37
D-tyrosine
random mutant enzyme C10-T183I, at pH 7.0 and 30°C
1.37
D-tyrosine
random mutant enzyme C10-T359M, at pH 7.0 and 30°C
1.63
D-tyrosine
random mutant enzyme 145-L330V, at pH 7.0 and 30°C
1.7
D-tyrosine
random mutant enzyme C10-F185Y, at pH 7.0 and 30°C
2.1
D-tyrosine
random mutant enzyme 145-V153A, at pH 7.0 and 30°C
26.7
Dopa
-
dopa oxidase activity
29.9
dopamine
-
pH 6.8, 10°C, in methanol-glycerol cryosolvent
61
dopamine
recombinant enzyme, pH 7.2, 37°C
133.2
dopamine
-
pH 6.8, 25°C, in methanol-glycerol cryosolvent
135
dopamine
-
inhibitor is phenylthiourea
144
dopamine
-
inhibitor is mimosine
210
dopamine
recombinant enzyme, pH 7.2, 37°C
433
dopamine
-
pH 6.8, 25°C, in methanol-glycerol cryosolvent
439
dopamine
-
pH 6.8, 25°C, in aqueous buffer
2540
dopamine
pH 6.8, 25°C, recombinant enzyme
123
esculetin
-
-
551
esculetin
-
(kcat as a kinetic constant) of the PPO/O2/ESC system at pH 4.5
928
esculetin
-
(kcat as a kinetic constant) of the PPO/O2/ESC system at pH 7
3
Gly-Gly-L-Tyr
-
in 0.1M sodium phosphate buffer (pH 7.0) at 25°C
7.2
Gly-Gly-L-Tyr
-
in 0.1M sodium phosphate buffer (pH 7.0) at 25°C
3.1
Gly-L-Tyr-Gly
-
in 0.1M sodium phosphate buffer (pH 7.0) at 25°C
4.2
Gly-L-Tyr-Gly
-
in 0.1M sodium phosphate buffer (pH 7.0) at 25°C
0.04
L-Dopa
-
pH 6.8, 25°C, in methanol-glycerol cryosolvent
1.8
L-Dopa
Helix vulgaris
-
-
7.18
L-Dopa
-
mutant enzyme R209H, in 50 mM Tris-HCl buffer pH 7.0, 0.01 mM CuSO4, 28°C
10.1
L-Dopa
-
in 50 mM potassium phosphate buffer (pH 7.0)
10.59
L-Dopa
-
wild type enzyme, in 50 mM Tris-HCl buffer pH 7.0, 0.01 mM CuSO4, 28°C
21
L-Dopa
wild type enzyme, in 50 mM Tris HCl buffer pH 7.5, 0.01 mM CuSO4, at 28°C
21.3
L-Dopa
-
in 50 mM potassium phosphate buffer (pH 7.0), with 30% (v/v) DMSO
31.1
L-Dopa
mutant enzyme V218F, in 50 mM Tris HCl buffer pH 7.5, 0.01 mM CuSO4, at 28°C
38.1
L-Dopa
recombinant enzyme, pH 7.2, 37°C
42
L-Dopa
-
pH 6.8, 10°C, in methanol-glycerol cryosolvent
72.12
L-Dopa
-
pH 5.0, 25°C
73.3
L-Dopa
mutant enzyme V218G, in 50 mM Tris HCl buffer pH 7.5, 0.01 mM CuSO4, at 28°C
75
L-Dopa
Vibrio tyrosinaticus
-
isoenzyme A
90
L-Dopa
Vibrio tyrosinaticus
-
isoenzyme B
107.4
L-Dopa
-
pH 6.8, 25°C, in aqueous buffer
141.1
L-Dopa
-
pH 6.8, 25°C, in methanol-glycerol cryosolvent
197
L-Dopa
recombinant enzyme, pH 7.2, 37°C
199.3
L-Dopa
pH 7.0, 25°C
880
L-Dopa
-
His6-tagged TYRC
1810
L-Dopa
pH 6.8, 25°C, recombinant enzyme
57
L-dopa methyl ester
recombinant enzyme, pH 7.2, 37°C
187
L-dopa methyl ester
recombinant enzyme, pH 7.2, 37°C
2.28
L-isoproterenol
recombinant enzyme, pH 7.2, 37°C
5.8
L-isoproterenol
recombinant enzyme, pH 7.2, 37°C
7.9
L-Tyr
-
-
3.2
L-Tyr-Gly-Gly
-
in 0.1M sodium phosphate buffer (pH 7.0) at 25°C
4
L-Tyr-Gly-Gly
-
in 0.1M sodium phosphate buffer (pH 7.0) at 25°C
2.5
L-tyrosinase
Mushroom
-
under 100 kPa O2
-
19.5
L-tyrosinase
Mushroom
-
under 21 kPa O2
-
0.576
L-tyrosine
-
at pH 8.0 and 37°C
0.92
L-tyrosine
random mutant enzyme RV145, at pH 7.0 and 30°C
1.03
L-tyrosine
random mutant enzyme RVC10, at pH 7.0 and 30°C
1.24
L-tyrosine
random mutant enzyme C10-N322S, at pH 7.0 and 30°C
1.29
L-tyrosine
-
wild type enzyme, in 50 mM Tris-HCl buffer pH 7.0, 0.01 mM CuSO4, 28°C
1.42
L-tyrosine
wild type enzyme, at pH 7.0 and 30°C
2.24
L-tyrosine
-
mutant enzyme R209H, in 50 mM Tris-HCl buffer pH 7.0, 0.01 mM CuSO4, 28°C
2.5
L-tyrosine
-
in 50 mM potassium phosphate buffer (pH 7.0)
2.6
L-tyrosine
recombinant enzyme, pH 7.2, 37°C
3.33
L-tyrosine
-
tyrosine hydroxylase activity
3.77
L-tyrosine
pH 6.8, 25°C, recombinant enzyme
4
L-tyrosine
wild type enzyme, in 50 mM Tris HCl buffer pH 7.5, 0.01 mM CuSO4, at 28°C
7.9
L-tyrosine
-
pH 7.0, 25°C
7.9
L-tyrosine
recombinant enzyme, pH 7.2, 37°C
16.7
L-tyrosine
mutant enzyme V218G, in 50 mM Tris HCl buffer pH 7.5, 0.01 mM CuSO4, at 28°C
20.8
L-tyrosine
pH 7.0, 25°C
44.1
L-tyrosine
mutant enzyme V218F, in 50 mM Tris HCl buffer pH 7.5, 0.01 mM CuSO4, at 28°C
100
L-tyrosine
Vibrio tyrosinaticus
-
isoenzyme A and B
3.4
L-tyrosine methyl ester
-
-
235
L-tyrosine methyl ester
-
-
2.24
methyl 3-hydroxy-L-tyrosinate
-
pH 6.8, 10°C, in methanolglycerol cryosolvent
3.4
methyl 3-hydroxy-L-tyrosinate
-
pH 6.8, 25°C, in aqueous buffer
8.9
methyl 3-hydroxy-L-tyrosinate
-
pH 6.8, 25°C, in methanolglycerol cryosolvent
2.66
o-Diphenol
-
Rapana venosa native (didecamers)
3.5
o-Diphenol
-
Rapana venosa RvH2 (subunits)
3.2
phenol
-
-
11.3
phenol
pH 6.8, 25°C, recombinant enzyme
12.7
phenol
-
pH 7.0, 25°C
14.36
phenol
-
pH and temperature not specified in the publication
8.1
protocatechuic acid
-
-
860
protocatechuic acid
-
-
1.5
Protocatechuic aldehyde
-
-
336
Protocatechuic aldehyde
-
-
9.7
pyrogallol
-
-
1.9
tyramine
-
pH 6.8, 10°C, in methanol-glycerol cryosolvent
2.88
tyramine
-
pH 5.0, 25°C
5
tyramine
-
inhibitor is mimosine
5
tyramine
-
inhibitor is phenylthiourea
7.4
tyramine
-
pH 6.8, 25°C, in methanol-glycerol cryosolvent
15.6
tyramine
pH 6.8, 25°C, recombinant enzyme
25.9
tyramine
-
pH 6.8, 25°C, in aqueous buffer
0.0117
tyrosine
-
enzyme from malignant melanocytes
0.0217
tyrosine
-
enzyme from normal melanocytes