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1.14.15.8: steroid 15beta-monooxygenase

This is an abbreviated version!
For detailed information about steroid 15beta-monooxygenase, go to the full flat file.

Word Map on EC 1.14.15.8

Reaction

progesterone
+
reduced ferredoxin
+
O2
+
H+
=
15beta-hydroxyprogesterone
+
oxidized ferredoxin
+
H2O

Synonyms

15beta-hydroxylase, 15beta-hydroxylase CYP106A2, BmCYP106A2, Cyp106A1, CYP106A2, cytochrome P-450meg, cytochrome P450meg, steroid-15-beta-monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.8 steroid 15beta-monooxygenase

KM Value

KM Value on EC 1.14.15.8 - steroid 15beta-monooxygenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.037 - 0.093
11-deoxycortisol
0.56
17alpha-hydroxyprogesterone
-
22°C
0.45
20alpha-dihydroprogesterone
-
22°C
0.625
4-androstene-3,17-dione
-
22°C
0.095
corticosterone
-
22°C
0.0012 - 0.06
deoxycorticosterone
0.0007 - 0.251
progesterone
0.00314
reduced ferredoxin
pH 7.4, 30°C, wild-type ferredoxin from the cyanobacterium Anabaena PCC 7119
0.00734
reduced flavodoxin
pH 7.4, 30°C, wild-type flavodoxin from the cyanobacterium Anabaena PCC 7119
1.11
testosterone
-
22°C
additional information
additional information
-