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1.14.14.33: ethylenediaminetetraacetate monooxygenase

This is an abbreviated version!
For detailed information about ethylenediaminetetraacetate monooxygenase, go to the full flat file.

Reaction

ethylenediaminetetraacetate
+ 2 FMNH2 + 2 O2 =
ethylenediamine-N,N'-diacetate
+ 2 glyoxylate + 2 FMN + 2 H2O

Synonyms

EmoA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.33 ethylenediaminetetraacetate monooxygenase

Engineering

Engineering on EC 1.14.14.33 - ethylenediaminetetraacetate monooxygenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
E70A
complete loss of activtiy
P291A
74.4% of wild-type activity
Q294A
85.6% of wild-type activity
Q58A
51.3% of wild-type activity
R68A
85.3% of wild-type activity
W11A
26.4% of wild-type activity
Y71A
complete loss of activtiy