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BRENDA support

1.14.14.25: cholesterol 24-hydroxylase

This is an abbreviated version!
For detailed information about cholesterol 24-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.25

Reaction

cholesterol
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(24S)-cholest-5-ene-3beta,24-diol
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

24S-hydroxylase, CH24H, cholesterol 24-hydroxylase, cholesterol 24-monooxygenase, cholesterol 24S hydroxylase, cholesterol 24S-hydroxylase, cholesterol hydroxylase, cholesterol-24S-hydroxylase, CYP46, CYP46A, CYP46A1, cytochrome P-450 46A1, cytochrome P450 46A1, cytochrome P450 cholesterol 24-hydroxylase, EC 1.14.13.98

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.25 cholesterol 24-hydroxylase

Localization

Localization on EC 1.14.14.25 - cholesterol 24-hydroxylase

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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
truncated enzymes are distributed at about a 1:1 ratio between the membrane fraction and the cytosol in low ionic strength buffer, when expressed in Escherichia coli
Manually annotated by BRENDA team
-
of liver
Manually annotated by BRENDA team