1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

This is an abbreviated version!
For detailed information about 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase, go to the full flat file.

Reaction

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

Synonyms

3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase, HsaAB

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.12 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

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Results	in table
811	AA Sequence
1	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
2	General Information
1	Inhibitors
5	kcat/KM [mM/s]
5	KM Value [mM]
2	Natural Substrates/ Products (Substrates)
2	Organism
6	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
11	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Turnover Number [1/s]

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Reference on EC 1.14.14.12 - 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

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715515

Dresen, C.; Lin, L.Y.; D'Angelo, I.; Tocheva, E.I.; Strynadka, N.; Eltis, L.D.

A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism

J. Biol. Chem.

285

22264-22275

2010

Mycobacterium tuberculosis (P9WJA1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJA1)

20448045