1.14.13.92: phenylacetone monooxygenase

This is an abbreviated version!
For detailed information about phenylacetone monooxygenase, go to the full flat file.

Reaction

Synonyms

4-hydroxyacetophenone monooxygenase, Baeyer-Villiger monooxygenase, BVMO, EtaA, HAPMO, M-PAMO, More, PAMO, phenylacetone monooxygenase, Tf PAMO

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.92 phenylacetone monooxygenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
3	Activating Compound
413	AA Sequence
9	Application
1	CAS Registry Number
13	Cloned(Commentary)
38	Cofactor
2	Crystallization (Commentary)
9	General Information
2	General Stability
16	Inhibitors
42	kcat/KM [mM/s]
69	KM Value [mM]
1	Localization
1	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
6	Organic Solvent Stability
69	Organism
13	PDB ID
16	pH Optimum
3	pH Range
1	Posttranslational Modification
112	Protein Variants
10	Purification (Commentary)
7	Reaction
2	Reaction Type
29	Reference
3	Specific Activity [micromol/min/mg]
131	Substrates and Products (Substrate)
4	Subunits
49	Synonyms
1	Systematic Name
21	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]
62	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 1.14.13.92 - phenylacetone monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

phenylacetone,NADPH:oxygen oxidoreductase

A flavoprotein (FAD). NADH cannot replace NADPH as coenzyme. In addition to phenylacetone, which is the best substrate found to date, this Baeyer-Villiger monooxygenase can oxidize other aromatic ketones [1-(4-hydroxyphenyl)propan-2-one, 1-(4-hydroxyphenyl)propan-2-one and 3-phenylbutan-2-one], some alipatic ketones (e.g. dodecan-2-one) and sulfides (e.g. 1-methyl-4-(methylsulfanyl)benzene).