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1.14.13.24: 3-hydroxybenzoate 6-monooxygenase

This is an abbreviated version!
For detailed information about 3-hydroxybenzoate 6-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.24

Reaction

3-hydroxybenzoate
+
NADH
+
H+
+
O2
=
2,5-Dihydroxybenzoate
+
NAD+
+
H2O

Synonyms

3-HBA-6-hydroxylase, 3-hydroxybenzoate 6-hydroxylase, 3-hydroxybenzoate-6-hydroxylase, 3-hydroxybenzoic acid-6-hydroxylase, 3HB6H, m-hydroxybenzoate 6-hydroxylase, MNX2, Mnx2p, NagX, NarX, Ncgl2923, oxygenase, 3-hydroxybenzoate 6-mono-, XlnD

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.24 3-hydroxybenzoate 6-monooxygenase

Inhibitors

Inhibitors on EC 1.14.13.24 - 3-hydroxybenzoate 6-monooxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cibacron blue
-
50% inhibition at 0.04 mM
Co2+
-
inhibits the enzyme activity at 0.5 mM by about 30%
diethylpyrocarbonate
Fe3+
-
inhibits the enzyme activity at 0.5 mM by about 50%
Mg2+
-
inhibits the enzyme activity at 0.5 mM by about 50%
Mn2+
complete inhibition at 5 mM
N-bromosuccinimide
p-chloromercuribenzoate
-
at low concentrations
Phenylglyoxal
Urea
-
70% loss of activity at 1 M