1.14.13.222: aurachin C monooxygenase/isomerase

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For detailed information about aurachin C monooxygenase/isomerase, go to the full flat file.

Reaction

Synonyms

auaG, aurachin C monooxygenase, MimA, MimABCD, Msmeg_1971

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.222 aurachin C monooxygenase/isomerase

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Results	in table
26	AA Sequence
2	Cloned(Commentary)
5	Cofactor
4	General Information
2	Metals/Ions
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
6	Organism
3	Pathway
3	Reaction
6	Reference
9	Substrates and Products (Substrate)
9	Synonyms
1	Systematic Name

Reaction

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Reaction on EC 1.14.13.222 - aurachin C monooxygenase/isomerase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide

(1b)

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aurachin C + NAD(P)H + H+ + O2 = 2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one + NAD(P)+ + H2O

(1a)

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aurachin C + NAD(P)H + H+ + O2 = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD(P)+ + H2O

overall reaction

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