1.14.13.22: cyclohexanone monooxygenase
This is an abbreviated version!
For detailed information about cyclohexanone monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.22
-
1.14.13.22
-
baeyer-villiger
-
acinetobacter
-
lactones
-
bvmos
-
ncimb
-
calcoaceticus
-
cyclohexanol
-
synthesis
-
criegee
-
epsilon-caprolactone
-
c4a-peroxyflavin
-
biooxidation
-
bicyclo3.2.0hept-2-en-6-one
-
phenylacetone
-
cyclopentanone
-
biotechnology
- 1.14.13.22
-
baeyer-villiger
- acinetobacter
- lactones
-
bvmos
-
ncimb
- calcoaceticus
- cyclohexanol
- synthesis
-
criegee
- epsilon-caprolactone
-
c4a-peroxyflavin
-
biooxidation
-
bicyclo3.2.0hept-2-en-6-one
- phenylacetone
- cyclopentanone
- biotechnology
Reaction
Synonyms
Bpro_556, CAMO, CHMO, ChnB, chnB protein, chnB1 protein, CHXON, CMO, cycloalkaone monooxygenase, cyclohexanone 1, 2-mono-oxygenase, cyclohexanone mono-oxygenase, cyclohexanone monooxygenase, cyclohexanone oxygenase, cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming), oxygenase, cyclohexanone mono-
ECTree
Advanced search results
Crystallization
Crystallization on EC 1.14.13.22 - cyclohexanone monooxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
structure of variant F246Y/K326C/L426F/F432L/T433A/L435S/S438I/F505L complexed with FAD, to 2.2 A resolution
-
enzyme in complex with FAD and NADP+ in 2 distinct states, hanging drop or sitting drop vapor diffusion methods, crystal form I with 0.2 M sodium acetate trihydrate, 0.1 M sodium cacodylate pH 6.5, and 30% PEG 8000, for crystal form II with 0.2 M magnesium acetate tetrahydrate, 0.1 M sodium cacodylate pH 6.5, and 20% PEG 8000
sitting drop vapor diffusion method. Two crystal structures of cyclohexanone monooxygenase with its product, epsilon-caprolactone, bound: the CHMO(Tight) and CHMO(Loose) structures. The CHMO(Tight) structure represents the enzyme state in which substrate acceptance and stereospecificity is determined, providing a foundation for engineering BVMOs with altered substrate spectra and/or stereospecificity. The CHMO(Loose) structure is the first structure where the product is solvent accessible. This structure represents the enzyme state upon binding and release of the substrate and product