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1.14.13.215: protoasukamycin 4-monooxygenase

This is an abbreviated version!
For detailed information about protoasukamycin 4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.215

Reaction

protoasukamycin
+
NADH
+
H+
+
O2
=
4-hydroxyprotoasukamycin
+
NAD+
+
H2O

Synonyms

asuE1, flavin-dependent protoasukamycin hydroxylase, protoasukamycin 4-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.215 protoasukamycin 4-monooxygenase

Reference

Reference on EC 1.14.13.215 - protoasukamycin 4-monooxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rui, Z.; Sandy, M.; Jung, B.; Zhang, W.
Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites
Chem. Biol.
20
879-887
2013
Streptomyces nodosus (D7P5V0), Streptomyces nodosus ATCC 29757 (D7P5V0)
Manually annotated by BRENDA team
Rui, Z.; Petrickova, K.; Skanta, F.; Pospisil, S.; Yang, Y.; Chen, C.Y.; Tsai, S.F.; Floss, H.G.; Petricek, M.; Yu, T.W.
Biochemical and genetic insights into asukamycin biosynthesis
J. Biol. Chem.
285
24915-24924
2010
Streptomyces nodosus (D7P5V0), Streptomyces nodosus
Manually annotated by BRENDA team