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1.14.13.182: 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

This is an abbreviated version!
For detailed information about 2-heptyl-3-hydroxy-4(1H)-quinolone synthase, go to the full flat file.

Reaction

2-heptyl-4(1H)-quinolone
+
NADH
+
H+
+
O2
=
2-heptyl-3-hydroxy-4(1H)-quinolone
+
NAD+
+
H2O

Synonyms

2-heptyl-3,4-dihydroxyquinoline synthase, Aqm, PqsH

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

Expression

Expression on EC 1.14.13.182 - 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression is influenced by the las/rhl systems. Pseudomonas quinolone signal synthesis might be regulated by the balance between the expression of the pqsA-D/phnAB, pqsH, antABC, and catBCA gene loci
-
farnesol suppresses the transcription and protein expression. Farnesol inhibits the expression of PQS signal synthase coding genes (pqsABCDE and pqsH) in the PQS system, but does not inhibit the expression of the PQS signal receptor coding gene pqsR