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1.14.12.17: nitric oxide dioxygenase

This is an abbreviated version!
For detailed information about nitric oxide dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.17

Reaction

2 nitric oxide + 2 O2 +

NAD(P)H
= 2 nitrate +
NAD(P)+
+
H+

Synonyms

barley hemoglobin, Cygb, cytoglobin, FHb1, flavoHb, flavohemoglobin, HbN, hemoglobin N, nitric oxide dioxygenase, nitric-oxide dioxygenase, NO degrading dioxygenase, NO dioxygenase, NOD, SHP, sphaeroides haem protein, type I flavohemoglobin, VHb, Vitreoscilla hemoglobin

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.17 nitric oxide dioxygenase

Engineering

Engineering on EC 1.14.12.17 - nitric oxide dioxygenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Y126F
-
mutant, displays little change in oxygen affinity indicating a crucial role of Tyr95 in protein function
Y126L
-
mutant, displays little change in oxygen affinity indicating a crucial role of Tyr95 in protein function
Y95F
-
mutant, enzyme shows no stable oxyform and nitric oxide dioxygenase activity
Y95L
-
mutant, enzyme shows no stable oxyform and nitric oxide dioxygenase activity