Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.11.53: mRNA N6-methyladenine demethylase

This is an abbreviated version!
For detailed information about mRNA N6-methyladenine demethylase, go to the full flat file.

Word Map on EC 1.14.11.53

Reaction

N6-methyladenine in mRNA
+
2-oxoglutarate
+
O2
=
adenine in mRNA
+
formaldehyde
+
succinate
+
CO2

Synonyms

AlkB homolog 5, ALKBH10B, ALKBH5, ALKBH5 demethylase, ALKBH9B, alkylation repair homolog protein 5, fat mass and obesity-associated enzyme, fat mass and obesity-associated protein, FTO, m6A mRNA demethylase, m6A RNA demethylase, m6A-RNA demethylase, N6-methyladenosine demethylase, RNA N6-methyladenine demethylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.53 mRNA N6-methyladenine demethylase

Purification

Purification on EC 1.14.11.53 - mRNA N6-methyladenine demethylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
DE52 column chromatography, Ni-NTA column chromatography, and Superdex 200 gel filtration
-
Ni affinity column chromatography, HiTrap Q column chromatography, and Superdex 75 gel filtration
-
Ni-NTA column chromatography, MonoS column chromatography, and Superdex 200 gel filtration
Ni-NTA His-Bind resin column chromatography, Source 15S column chromatography, and Superdex 200 gel filtration
-