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1.14.11.15: gibberellin 3beta-dioxygenase

This is an abbreviated version!
For detailed information about gibberellin 3beta-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.15

Reaction

gibberellin 20
+
2-oxoglutarate
 +
O2
=
gibberellin 1
 +
succinate
 +
CO2

Synonyms

(giberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating), AtGA3ox1, CYP115, DWARF1 D1 protein, DWF1, GA 3-oxidase, GA 3-oxidase 2, GA 3beta-hydroxylase, GA 3ox, GA3 oxidase, GA3 oxidase 1, GA3-oxidase, GA3-oxidase 1, GA3ox, GA3ox1, GA3OX4, gibberellin 3 oxidase, gibberellin 3 oxidase 1, gibberellin 3-beta-dioxygenase 1, gibberellin 3-beta-dioxygenase 2-1, gibberellin 3-beta-dioxygenase 2-2, gibberellin 3-beta-dioxygenase 2-3, gibberellin 3-oxidase, gibberellin 3-oxidase 1, gibberellin 3-oxidase 2, gibberellin 3beta dioxygenase, gibberellin 3beta-hydroxylase, MtGA3ox1, OsGA3ox1, oxygenase, gibberellin 3beta-di-, SbGA3ox2, SSL, TfGA3ox1, ZmGA3ox2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.15 gibberellin 3beta-dioxygenase

Inhibitors

Inhibitors on EC 1.14.11.15 - gibberellin 3beta-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
13-O-acetyl-16,17-dihydrogibberellin A5
-
competitive, 50% inhibition of activity with gibberellin A20: 0.008 mM
13-O-acetylgibberellin A5
-
competitive, 50% inhibition of activity with gibberellin A20: 0.004 mM
16,17-dihydrogibberellin A20
-
competitive, 50% inhibition of activity with gibberellin A20: 0.05 mM
16,17-dihydrogibberellin A5
-
competitive, 50% inhibition of activity with gibberellin A20: 0.192 mM
16-deoxo-2,3-di-dehydro-3-methyl-deoxygibberellin C
-
-
16-Deoxo-deoxygibberellin C
17-ethyl-16,17-dihydrogibberellin A5
-
competitive, 50% inhibition of activity with gibberellin A20: 0.009 mM
17-methyl-16,17-dihydrogibberellin A5
-
competitive, 50% inhibition of activity with gibberellin A20: 0.002 mM
17-n-propyl-16,17-dihydrogibberellin A5
-
competitive, 50% inhibition of activity with gibberellin A20: 0.007 mM
2,2'-bipyridyl
-
-
2,3-didehydro-3-methyl-deoxygibberellin C
-
-
2,3-didehydro-3-methyl-gibberellin a9
2,3-dimethyl-gibberellin a5
-
-
3-methyl-gibberellin a5
-
-
Cd2+
-
0.5 mM, strong
Co2+
-
0.5 mM, strong
Cu2+
-
0.5 mM, strong
deoxygibberellin C
endo-16,17-dihydro gibberellin A5
-
competitive inhibitor of 3beta-hydroxylation of gibberellin A20
exo-16,17-dihydro gibberellin A20
-
competitive inhibitor of 3beta-hydroxylation of gibberellin A20
exo-16,17-dihydro gibberellin A5
-
competitive inhibitor of 3beta-hydroxylation of gibberellin A20
gibberellin
-
the enzyme is negatively feedback regulated by high total active gibberellin levels
gibberellin a15
-
inhibits 3beta-hydroxylation of gibberellin a20
gibberellin a20
gibberellin a4
-
treatment causes down-regulation of gibberellin-insensitive dwarf 1, gibberellin A20 oxidase, and gibberellin 3beta-dioxygenase as well as degradation of DELLA1 protein
gibberellin a44
-
inhibits 3beta-hydroxylation of gibberellin a20
gibberellin a5
gibberellin a9
-
inhibits 3beta-hydroxylation of gibberellin a20
Hg2+
-
0.5 mM, strong
Hydrocinnamic acid
indole acetic acid
indole propionic acid
Mn2+
-
0.5 mM, strong
Ni2+
-
0.5 mM, strong
trinexapac ethyl
-
competitive, 50% inhibition of activity with gibberellin A20: 0.3 mM
Zn2+
-
0.5 mM, strong
additional information
-