1.13.12.7: firefly luciferase
This is an abbreviated version!
For detailed information about firefly luciferase, go to the full flat file.
Word Map on EC 1.13.12.7
-
1.13.12.7
-
bioluminescence
-
luminescence
-
chemiluminescence
-
emit
-
renilla
-
noninvasive
-
luciferases
-
cypridina
-
photon
-
lentiviral
-
adenovirus
-
click
-
luciferase-expressing
-
herpes
-
engraft
-
nude
-
co-transfected
-
cytomegalovirus
-
camera
-
electroporation
-
simplex
-
hsp70
-
emitter
-
replication-deficient
-
excited-state
-
promoter-driven
-
charge-coupled
-
nonviral
-
nanoluc
-
non-invasively
-
gaussia
-
luminol
-
intramyocardial
-
coelenterazine
-
bicistronic
-
yellow-green
-
molecular biology
-
light-emitting
-
cap-independent
-
aequorin
-
biotechnology
-
red-shifted
-
dnaj
-
luminometer
-
grpe
-
polyethylenimine
-
bioimaging
-
luciferase-based
-
medicine
-
photoproteins
-
glow
-
analysis
-
multicolor
-
brighter
- 1.13.12.7
-
bioluminescence
-
luminescence
-
chemiluminescence
-
emit
- renilla
-
noninvasive
- luciferases
- cypridina
-
photon
-
lentiviral
- adenovirus
-
click
-
luciferase-expressing
-
herpes
-
engraft
-
nude
-
co-transfected
- cytomegalovirus
-
camera
-
electroporation
- simplex
- hsp70
-
emitter
-
replication-deficient
-
excited-state
-
promoter-driven
-
charge-coupled
-
nonviral
- nanoluc
-
non-invasively
- gaussia
- luminol
-
intramyocardial
- coelenterazine
-
bicistronic
-
yellow-green
- molecular biology
-
light-emitting
-
cap-independent
- aequorin
- biotechnology
-
red-shifted
- dnaj
-
luminometer
- grpe
- polyethylenimine
-
bioimaging
-
luciferase-based
- medicine
-
photoproteins
-
glow
- analysis
-
multicolor
-
brighter
Reaction
Synonyms
AL1, AL2, beetle luciferase, CBG99luc, CBRluc, FFL, firefly luciferase, firefly luciferin luciferase, fluc, LpLuc1, LpLuc2, Luc, Luc1, Luc1-type luciferase, Luc2, Luc2-type luciferase, luciferase, luciferase (firefly luciferin), luciferase FM, luciferin, Luciola italica luciferase, lucPpe, lucPpy, orange light-producing luciferase, oxygen 4-oxidoreductase, PC3-Luc, Photinus luciferin 4-monooxygenase (ATP-hydrolyzing), Photinus pyralis luciferase, PML, PpLase, Ppy, Ppy GR-TS, Ppy RE-TS, PpyWT, PsntWT
ECTree
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IC50 Value
IC50 Value on EC 1.13.12.7 - firefly luciferase
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0.0004
(2E)-1-(1-benzofuran-2-yl)-3-(4-methylphenyl)prop-2-en-1-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0018
(2E)-1-(1-benzofuran-2-yl)-3-phenylprop-2-en-1-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00007
(2E)-1-(2-hydroxyphenyl)-3-(4-methylphenyl)prop-2-en-1-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0011
(2E)-1-(5-chlorothiophen-2-yl)-3-(4-methylphenyl)prop-2-en-1-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00041
(2E)-1-(5-chlorothiophen-2-yl)-3-phenylprop-2-en-1-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000088
(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
0.0002
(2E)-2-[(2-bromophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00009
(2E)-2-[(2-chlorophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0005
(2E)-2-[(2-methoxyphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00044
(2E)-2-[(2-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0013
(2E)-2-[(2-nitrophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0006
(2E)-2-[(3-bromophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0014
(2E)-2-[(3-chlorophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000034
(2E)-2-[(3-methoxyphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0015
(2E)-2-[(3-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0011
(2E)-2-[(3-nitrophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000007
(2E)-2-[(4-bromophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00006
(2E)-2-[(4-chlorophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000007
(2E)-2-[(4-ethoxyphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0000012
(2E)-2-[(4-ethylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000031
(2E)-2-[(4-fluorophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one, (2E)-2-[(4-hydroxyphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0000012
(2E)-2-[(4-methoxyphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0000005
(2E)-2-[(4-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000056
(2E)-2-[(4-nitrophenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0109
(2E)-2-[(pyridin-3-yl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00013
(2E)-2-[[4-(benzyloxy)phenyl]methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000049
(2E)-2-[[4-(diethylamino)phenyl]methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0000005
(2E)-2-[[4-(dimethylamino)phenyl]methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0002
(2E)-2-[[4-(dimethylamino)phenyl]methylidene]-6-methoxy-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0012
(2E)-2-[[4-(dimethylamino)phenyl]methylidene]-7-methoxy-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.007
(2E)-2-[[4-(dimethylamino)phenyl]methylidene]-8-methoxy-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000012
(2E)-2-[[4-(methylsulfanyl)phenyl]methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00026
(2E)-2-[[4-(trifluoromethyl)phenyl]methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00014
(2E)-5-methoxy-2-[(4-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.000159
(2E)-6-methoxy-2-[(4-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00286 - 122
(2E)-7-methoxy-2-[(4-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
-
0.000106
(2E)-8-methoxy-2-[(4-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0002
(2R)-2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]propanoic acid
Photinus pyralis
-
0.00008
(2Z)-3-[(2-bromophenyl)amino]-1-pyridin-2-ylprop-2-en-1-one
Photinus pyralis
-
0.00021
(2Z)-3-[[4-(dimethylamino)cyclohexa-1,5-dien-1-yl]amino]-1-phenylprop-2-en-1-one
Photinus pyralis
-
0.0008
(3Z)-3-[[4-(dimethylamino)phenyl]methylidene]-1,3-dihydro-2H-indol-2-one
Photinus pyralis
-
0.00000025
(6E)-6-[(3-carboxy-4-hydroxyphenyl)methylidene]-5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
Photinus pyralis
pH and temperature not specified in the publication
-
0.002
(7E)-7-[(4-methylphenyl)methylidene]-8-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
Photinus pyralis
pH and temperature not specified in the publication
-
0.00032
2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3(2H)-yl)-1-(4-methylphenyl)ethanone
Photinus pyralis
-
0.0013
2-(4-ethoxyphenyl)-4-[(4-methylpiperazin-1-yl)carbonyl]quinoline
Photinus pyralis
-
0.00041
2-(4-ethoxyphenyl)-4-[(4-pyridin-2-ylpiperazin-1-yl)carbonyl]quinoline
Photinus pyralis
-
0.004
2-(4-methylphenyl)-4-[(4-pyrimidin-2-ylpiperazin-1-yl)carbonyl]quinoline
Photinus pyralis
-
0.0073
2-([7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00016
2-benzylidene-1H-indene-1,3(2H)-dione
Photinus pyralis
pH and temperature not specified in the publication
-
0.00056
2-hydroxy-5-[(E)-(1-oxo-3,4-dihydronaphthalen-2(1H)-ylidene)methyl]benzoic acid
Photinus pyralis
pH and temperature not specified in the publication
-
0.0008
2-hydroxy-N'-[(1E)-(2-hydroxyphenyl)methylidene]benzohydrazide
Photinus pyralis
-
0.000063
2-[(4-methylphenyl)methylidene]-1H-indene-1,3(2H)-dione
Photinus pyralis
pH and temperature not specified in the publication
-
0.0024
2-[(4-methylphenyl)methyl]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00022
2-[5-(3-chloro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine
Photinus pyralis
-
0.0018
2-[[4-(dimethylamino)phenyl]methyl]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.00058
3-(4-methylphenyl)-4,5-dihydro-2H-benzo[g]indazole
Photinus pyralis
pH and temperature not specified in the publication
-
0.01471
3-([7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.0007
4-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(4-ethoxyphenyl)quinoline
Photinus pyralis
-
0.01076
4-(4-aminophenoxy)-7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Photinus pyralis
-
pH 7.8, 20°C
0.0059
4-(4-methylphenyl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Photinus pyralis
pH and temperature not specified in the publication
-
0.00012
4-([7-(2,2-dimethylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)-N,N-dimethylaniline
Photinus pyralis
-
pH 7.8, 20°C
0.00007
4-([7-(2,2-dimethylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)-N-methylaniline
Photinus pyralis
-
pH 7.8, 20°C
0.00008
4-([7-(2,2-dimethylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00012
4-([7-(2-methylprop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00031
4-([7-(2-methylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00753
4-([7-(3-methylbut-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00646
4-([7-(3-methylbutyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00224
4-([7-(prop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00036
4-([7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.0017
4-amino-6-[(E)-[4'-[(Z)-(8-amino-1-hydroxy-5,7-disulfonato-6,7-dihydronaphthalen-2-yl)diazenyl]-3-methylbiphenyl-4-yl]diazenyl]-5-hydroxy-2,3-dihydronaphthalene-1,3-disulfonate
Photinus pyralis
-
0.00029
4-[(7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00943
4-[(7-ethenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00351
4-[(7-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]aniline
Photinus pyralis
-
pH 7.8, 20°C
0.0003
4-[1-(1,3-benzothiazol-2-yl)-2-(4-methylpiperazin-1-yl)-2-oxoethyl]phenol
Photinus pyralis
-
0.000033
5'-O-[[2-(6-hydroxy-1,3-benzothiazol-2-yl)-1,3-thiazole-4-carbonyl]sulfamoyl]adenosine
Photinus pyralis
pH and temperature not specified in the publication
-
0.0003
5-(ethanesulfonyl)-2-(naphthalen-2-yl)-1,3-benzoxazole
Photinus pyralis
pH and temperature not specified in the publication
-
0.0011
5-methyl-N-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]thiophene-2-carboxamide
Photinus pyralis
-
0.0002
5-[(2E)-4-(4-bromophenyl)-4-oxobut-2-en-1-yl]-2-hydroxybenzoic acid
Photinus pyralis
pH and temperature not specified in the publication
-
0.00044
5-[(E)-(6-bromo-1-oxo-3,4-dihydronaphthalen-2(1H)-ylidene)methyl]-2-hydroxybenzoic acid
Photinus pyralis
pH and temperature not specified in the publication
-
0.135
D-luciferin
Photinus pyralis
-
inhibits CoA-ligase activity with L-luciferin, IC50: 0.135 mM against 0.1 mM L-luciferin
0.0009
ethyl 4-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonyl]piperazine-1-carboxylate
Photinus pyralis
-
0.0045
N'-(3-chlorophenyl)-N-[(1Z)-(3-chlorophenyl)methylidene]imidoformamide
Photinus pyralis
-
0.00009
N,N-dimethyl-4-([7-(2-methylprop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00018
N,N-dimethyl-4-([7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00065
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-methylfuran-3-carboxamide
Photinus pyralis
-
0.0012
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-methylfuran-3-carboxamide
Photinus pyralis
-
0.00006
N-methyl-4-([7-(2-methylprop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.00013
N-methyl-4-([7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy)aniline
Photinus pyralis
-
pH 7.8, 20°C
0.0007
N-[5-[(2,2-dimethylpropanoyl)amino]pyridin-2-yl]-3-hydroxybenzamide
Photinus pyralis
-
0.0011
N-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]thiophene-2-carboxamide
Photinus pyralis
-
0.001
NFkappaBAI4
Photinus pyralis
pH and temperature not specified in the publication
-
0.0005
[2-(4-ethoxyphenyl)quinolin-4-yl][4-(pyridin-2-yl)piperazin-1-yl]methanone
Photinus pyralis
pH and temperature not specified in the publication
-
0.00286
Photinus pyralis
pH and temperature not specified in the publication
-
122
(2E)-7-methoxy-2-[(4-methylphenyl)methylidene]-3,4-dihydronaphthalen-1(2H)-one
Photinus pyralis
pH and temperature not specified in the publication
-
0.0005
2-(2-fluorophenyl)-6-methoxy-1,3-benzothiazole
Photinus pyralis
pH and temperature not specified in the publication
0.00032
Photuris pensylvanica
-
-
0.0019
Photinus pyralis
pH and temperature not specified in the publication