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1.13.11.4: gentisate 1,2-dioxygenase

This is an abbreviated version!
For detailed information about gentisate 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.4

Reaction

2,5-Dihydroxybenzoate
+
O2
=
maleylpyruvate

Synonyms

2,5-dihydroxybenzoate dioxygenase, DsmD, EC 1.13.1.4, EC 1.99.2.4, eGDO, GDO, GDO-II, gdoA, GDOsp, GenH, gentisate dioxygenase, gentisate oxygenase, gentisate-1,2-dioxygenase, gentisic acid oxidase, gtdA-2, hbzE, Nagl1, Nagl2, Nagl3, NarI, oxygenase, gentisate 1,2-di-, P25X gentisate 1,2-dioxygenase, P35X gentisate 1,2-dioxygenase, salicylate 1,2-dioxygenase, SDO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.4 gentisate 1,2-dioxygenase

Turnover Number

Turnover Number on EC 1.13.11.4 - gentisate 1,2-dioxygenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.565 - 6.08
1-hydroxy 2 naphthoate
44
1-hydroxy-2-naphthoate
-
-
24
1-hydroxynaphthalene-2-carboxylic acid
-
wild-type enzyme, pH and temperature not specified in the publication
0.37 - 161.29
2,5-Dihydroxybenzoate
0.2
3,4-dichlorosalicylate
-
pH 8.0
0.02
3,5-Dibromosalicylate
-
pH 8.0
4
3-aminosalicylate
0.3
3-bromosalicylate
10.33
3-Chlorogentisate
-
pH 7.4, 30°C
0.4
3-chlorosalicylate
0.5
3-hydroxysalicylate
2.9
3-methylsalicylate
0.2
4-Aminosalicylate
pH 8.0, temperature not specified in the publication
0.7
4-bromosalicylate
-
pH 8.0
0.8
4-chlorosalicylate
0.2
4-hydroxysalicylate
0.3
4-methylsalicylate
2.8 - 59.3
5-Aminosalicylate
0.1
5-bromosalicylate
-
pH 8.0
0.5
5-chlorosalicylate
2.4 - 3.6
5-Fluorosalicylate
2.1 - 14.3
5-Methylsalicylate
94 - 642
gentisate
0.9 - 2.3
salicylate