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1.13.11.4: gentisate 1,2-dioxygenase

This is an abbreviated version!
For detailed information about gentisate 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.4

Reaction

2,5-Dihydroxybenzoate
+
O2
=
maleylpyruvate

Synonyms

2,5-dihydroxybenzoate dioxygenase, DsmD, EC 1.13.1.4, EC 1.99.2.4, eGDO, GDO, GDO-II, gdoA, GDOsp, GenH, gentisate dioxygenase, gentisate oxygenase, gentisate-1,2-dioxygenase, gentisic acid oxidase, gtdA-2, hbzE, Nagl1, Nagl2, Nagl3, NarI, oxygenase, gentisate 1,2-di-, P25X gentisate 1,2-dioxygenase, P35X gentisate 1,2-dioxygenase, salicylate 1,2-dioxygenase, SDO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.4 gentisate 1,2-dioxygenase

KM Value

KM Value on EC 1.13.11.4 - gentisate 1,2-dioxygenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.045 - 0.29
1,4-dihydroxy-2-naphthoate
0.0209
1-hydroxy 2 naphthoate
-
0.134
1-hydroxy-2-naphthoate
-
-
0.14
1-hydroxynaphthalene-2-carboxylic acid
-
wild-type enzyme, pH and temperature not specified in the publication
0.011 - 0.13
2,5-Dihydroxybenzoate
0.285
3,4-dichlorosalicylate
-
pH 8.0
0.14 - 7.7
3,4-Dimethylgentisate
0.094
3,5-Dibromosalicylate
-
pH 8.0
0.754
3,6-dichlorogentisate
-
-
2.3
3-aminosalicylate
0.011 - 0.33
3-Bromogentisate
0.071
3-bromosalicylate
0.036
3-Chlorogentisate
-
pH 7.4, 30°C
0.027
3-chlorosalicylate
0.01155 - 3.65
3-Ethylgentisate
0.035 - 0.08962
3-Fluorogentisate
0.067
3-hydroxysalicylate
0.0043 - 2.75
3-Isopropylgentisate
0.027 - 1.75
3-Methylgentisate
0.116
3-methylsalicylate
1.18
3-O-Methylgentisate
-
-
0.02326 - 0.24
4-Chlorogentisate
0.1
4-chlorosalicylate
0.015 - 0.044
4-Fluorogentisate
0.039
4-hydroxysalicylate
1.2 - 1.23
4-Isopropylgentisate
0.057 - 0.52
4-Methylgentisate
0.028
4-methylsalicylate
0.45
4-O-Methylgentisate
-
-
0.216 - 3.1
5-Aminosalicylate
0.126
5-bromosalicylate
-
pH 8.0
0.085
5-chlorosalicylate
0.047 - 0.99
5-Fluorosalicylate
0.328 - 0.788
5-Methylsalicylate
0.0071 - 0.167
gentisate
0.055 - 0.096
O2
0.012 - 0.017
salicylate
additional information
additional information
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