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1.13.11.28: 2,3-dihydroxybenzoate 2,3-dioxygenase

This is an abbreviated version!
For detailed information about 2,3-dihydroxybenzoate 2,3-dioxygenase, go to the full flat file.

Reaction

2,3-Dihydroxybenzoate
+
O2
=
2-carboxy-cis,cis-muconate

Synonyms

2,3-dihydroxybenzoate 2,3-oxygenase

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.28 2,3-dihydroxybenzoate 2,3-dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.28 - 2,3-dihydroxybenzoate 2,3-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
preincubation with substrate protects against inactivation
8-hydroxyquinoline
-
reversible by addition of Cu2+
arsenite
-
-
Cd2+
-
-
Co2+
-
-
diethyldithiocarbamate
-
reversible by addition of Cu2+
dithiothreitol
-
preincubation with substrate protects against inactivation
glutathione
iodoacetate
-
preincubation with substrate protects against inactivation
L-cysteine
-
preincubation with substrate protects against inactivation
N-ethylmaleimide
Neocuproine
-
reversible by addition of Cu2+
p-chloromercuribenzoate
Salicylaldoxime
-
reversible by addition of Cu2+
Semicarbazide
-
-
Sulfide
-
-