1.1.99.B6: phosphonoacetaldehyde reductase (acceptor)

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For detailed information about phosphonoacetaldehyde reductase (acceptor), go to the full flat file.

Reaction

Synonyms

FomC

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.99 With unknown physiological acceptors

                1.1.99.B6 phosphonoacetaldehyde reductase (acceptor)

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
1	Cofactor
1	General Information
1	kcat/KM [mM/s]
2	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
4	Organism
2	pH Optimum
1	Purification (Commentary)
1	Reaction
4	Reference
3	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.1.99.B6 - phosphonoacetaldehyde reductase (acceptor)

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2-hydroxyethylphosphonate + NADP+

phosphonoacetaldehyde + NADPH + H+

Streptomyces wedmorensis

-

-

712363

-

-

r

phosphonoacetaldehyde + reduced acceptor

2-hydroxyethylphosphonate + acceptor

Streptomyces fradiae

D2SNG2

fomC is required for production of fosfomycin

703183

-

-

?

additional information

?

-

Streptomyces wedmorensis

-

no reaction is observed with hydroxymethylphosphonate and 3-hydroxypropylphosphonate

712363

-

-

?